Dorival Martins, Dao Nguyen  Cell Chemical Biology 

Slides:



Advertisements
Similar presentations
SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.
Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.
Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:
LDAI-Based Chemical Labeling of Intact Membrane Proteins and Its Pulse-Chase Analysis under Live Cell Conditions Takayuki Miki, Sho-hei Fujishima, Kazuhiro.
How surgeons can find information online? Martin Hewitt International Journal of Surgery Volume 5, Issue 6, Pages (December 2007) DOI: /j.ijsu
Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.
Chemical Components of Cells
Optimizing Aminoglycoside Use
Volume 22, Issue 5, Pages v-vi (May 2015)
Ghrelin—a new player in glucose homeostasis?
Now Playing: Farnesol in the Biofilm
Enzyme Annotation with Chemical Tools
Boosting Bacterial Metabolism to Combat Antibiotic Resistance
Antibiotics: A New Hope
Foundations for Directed Alkaloid Biosynthesis
Microbiology: Social Suicide for a Good Cause
Nature’s Strategy for Catalyzing Diels-Alder Reaction
Chemical Proteomics of Host-Pathogen Interaction
Matthieu Desroses, Mikael Altun  Cell Chemical Biology 
In Search of the Missing Ligands for TetR Family Regulators
Adding Specificity to Artificial Transcription Activators
In This Issue Cell Volume 158, Issue 5, (August 2014)
Simon Haas, Andreas Trumpp  Developmental Cell 
Calendar Annals of Emergency Medicine
Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology
Volume 26, Issue 2, Pages (February 2018)
Screening Drugs for Kidney Disease: Targeting the Podocyte
A Noncanonical Path to Mechanism of Action
Bioactive Cell-Penetrating Peptides: Kill Two Birds with One Stone
No Need To Be Pure: Mix the Cultures!
Volume 152, Issue 1, (January 2013)
In vitro selection of antibiotic resistance in Pseudomonas aeruginosa
Resolving Resolvins Chemistry & Biology
Andy Weiss, Renee M. Fleeman, Lindsey N. Shaw  Cell Chemical Biology 
Volume 130, Issue 6, (September 2007)
Now Playing: Farnesol in the Biofilm
PARP Inhibitors: Staying on Target?
Antigen-Presenting Cells: Professionals and amateurs
Support Your Specialty
Volume 21, Issue 8, Pages v-vi (August 2014)
Foundations for Directed Alkaloid Biosynthesis
Discrimination between Two Endocannabinoids
Volume 143, Issue 6, (December 2010)
Volume 17, Issue 2, Pages (February 1950)
Volume 69, Issue 3, Pages (February 2006)
Targeting Antibiotic Tolerance, Pathogen by Pathogen
Nature’s Strategy for Catalyzing Diels-Alder Reaction
L-DOPA Ropes in tRNAPhe
Volume 21, Issue 9, Pages (September 2014)
Getting into Nursing Research
Volume 163, Issue 4, (November 2015)
Volume 4, Issue 1, Pages 2-3 (February 2006)
Volume 24, Issue 2, Pages (February 2017)
Anne C. Conibear, Markus Muttenthaler  Cell Chemical Biology 
Volume 163, Issue 2, (October 2015)
In Memoriam: E. Donnall Thomas
Volume 134, Issue 6, (September 2008)
Volume 21, Issue 9, Pages (September 2014)
In This Issue Cell Volume 145, Issue 3, (April 2011)
Volume 22, Issue 4, Pages vii-viii (April 2015)
Volume 148, Issue 1, (January 2012)
Presentation transcript:

Stimulating Central Carbon Metabolism to Re-sensitize Pseudomonas aeruginosa to Aminoglycosides  Dorival Martins, Dao Nguyen  Cell Chemical Biology  Volume 24, Issue 2, Pages 122-124 (February 2017) DOI: 10.1016/j.chembiol.2017.02.004 Copyright © 2017 Terms and Conditions

Figure 1 Fumarate and Glyoxylate Effects on Central Metabolism, Aminoglycoside Uptake and Killing Fumarate and glyoxylate cause different perturbations of central carbon metabolism, with divergent downstream effects on respiration, proton motive force (PMF), tobramycin uptake, and bacterial killing. Cell Chemical Biology 2017 24, 122-124DOI: (10.1016/j.chembiol.2017.02.004) Copyright © 2017 Terms and Conditions