Notch Signaling: Filopodia Dynamics Confer Robustness

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Presentation transcript:

Notch Signaling: Filopodia Dynamics Confer Robustness Marco Milán, Stephen M. Cohen  Current Biology  Volume 20, Issue 18, Pages R802-R804 (September 2010) DOI: 10.1016/j.cub.2010.07.030 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Long-range Notch signaling mediated by dynamic filopodia. (A) Thorax of an adult fly decorated by an ordered array of small mechanosensory bristles. Note the ordered spacing (image courtesy of Neus Rafel). (B) Cartoon depicting the spatial localization of the sensory organ precursors (SOPs, in red) within the epithelial sheet, which send long basal filopodia to mediate long-range Notch signaling. The upper image shows the epithelial sheet as seen from above, while the lower image shows a side-on view. Current Biology 2010 20, R802-R804DOI: (10.1016/j.cub.2010.07.030) Copyright © 2010 Elsevier Ltd Terms and Conditions