FIM total score by study visit (ITT population). FIM total score by study visit (ITT population). LOCF imputation was performed for the month 6 assessment using month 3 data; the number of patients analysed per visit is indicated. CMM, conventional medical management (arm); FIM, Functional Independence Measure ; ITB, intrathecal baclofen (arm); ITT, intention-to-treat; LOCF, last observation carried forward. Michael Creamer et al. J Neurol Neurosurg Psychiatry 2018;89:642-650 ©2018 by BMJ Publishing Group Ltd