coTCRcys-transduced T cells control tumor growth in vivo.

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coTCRcys-transduced T cells control tumor growth in vivo. coTCRcys-transduced T cells control tumor growth in vivo. NSG mice were injected with A*1101+ LMP2+ MDA-MB-231 tumor cells then treated with T-cell infusions (6 mice/group). Tumor size, measured by calipers (A) or bioluminescence (B), showed significant inhibition of tumor growth by coTCRcys-transduced T cells compared with mock-T cells. Bioluminescence images were taken 17 days after T-cell infusion. Yong Zheng et al. Cancer Immunol Res 2015;3:1138-1147 ©2015 by American Association for Cancer Research