Interaction of MAPJD with E-box sequence of the RIOK1 gene.

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Interaction of MAPJD with E-box sequence of the RIOK1 gene. Interaction of MAPJD with E-box sequence of the RIOK1 gene. A, positions of E-box motifs in the 5′ flanking region of the RIOK1 gene. B and C, sequence-specific binding of MAPJD to E-box motif, detected by EMSA. MAPJD or MYC protein was incubated with a DNA probe containing the E-box sequence in the genomic segment-7, with or without a competitor (B), as well as with or without anti-MAPJD or MYC antibody (C). Arrowheads, supershifted bands. Chie Suzuki et al. Mol Cancer Ther 2007;6:542-551 ©2007 by American Association for Cancer Research