8/22/2019 Exercise 1 In the ISwR data set alkfos, do a PCA of the placebo and Tamoxifen groups separately, then together. Plot the first two principal.

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8/22/2019 Exercise 1 In the ISwR data set alkfos, do a PCA of the placebo and Tamoxifen groups separately, then together. Plot the first two principal components of the whole group with color coding for the treatment and control subjects. Conduct a linear discriminant analysis of the two groups using the 7 variables. How well can you predict the treatment? Is this the usual kind of analysis you would see? Use logistic regression to predict the group based on the measurements. Compare the in-sample error rates. Use cross-validation with repeated training subsamples of 38/43 and test sets of size 5/43. What can you now conclude about the two methods? May 26, 2015 SPH 247 Statistical Analysis of Laboratory Data

Exercise 2 In the ISwR data set alkfos, cluster the data based on the 7 measurements using hclust(), kmeans(), and Mclust(). Compare the 2-group clustering with the placebo/Tamoxifen classification. May 26, 2015 SPH 247 Statistical Analysis of Laboratory Data