Parenchymal, nonparenchymal, and immune cells of the liver and their role in metastasis. Parenchymal, nonparenchymal, and immune cells of the liver and their role in metastasis. Listed are the parenchymal and nonparenchymal cells of the liver and their anti- and prometastatic functions. Symbols shown for each cell type were used to depict intercellular communications in Figs. 1 and 2. EMT, epithelial-mesenchymal transition; Treg, regulatory T cell. Pnina Brodt Clin Cancer Res 2016;22:5971-5982 ©2016 by American Association for Cancer Research