ZCWPW1 expression and dynamic localization in meiotic germ cells

Slides:

Advertisements

Similar presentations

Fig. 5 Correlation of RNA expression and protein abundance.

Advertisements

Fig. 2 Transport properties of a BP transistor at low temperature.

Fig. 4 Ballistic simulation of BP FETs.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Evolution of magnetic field lines around a foreshock bubble in the GSE-XY plane (z = 0): Results of a hybrid simulation. Evolution of magnetic field.

Fig. 1 Map of water stress and shale plays.

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

HT synthesis of boronic acids using the building block approach

Fig. 6 Comparison of properties of water models.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 3 Hippocampal theta oscillations during goal-directed navigation.

Fig. 2 Reference-fixing experiment, results.

Fig. 2 Ferroelectric domains resolved in WTe2 single crystals.

Fig. 3 Scan rate effects on the layer edge current.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 1 Reference-fixing experiment, setup.

Fig. 1 Bioinspired design of AAD for promoting wound contraction.

Fig. 1 Distribution of total and fake news shares.

Fig. 3 Photon number statistics resulting from Fock state |l, S − l〉 interference. Photon number statistics resulting from Fock state |l, S − l〉 interference.

Fig. 2 2D QWs of different propagation lengths.

Fig. 5 Molecular dynamics simulations of Rac1.

Electronic structure of the oligomer (n = 8) at the UB3LYP/6-31G

Fig. 4 EUV TG signal from Si.

Fig. 4 DFT ωB97x/def2-TZVPP atomic charges on the sulfur atom of substituted thioaldehyde and AIMNet prediction with a different number of iterative passes.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 4 OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with different pH. OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 4 The mechanical performances of thermally stable click-ionogels.

Fig. 4 Evolution of fraction of sickled RBCs under hypoxia.

Fig. 4 Demonstration of dynamic scale invariance at long times.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 6 Global sensitivity analysis illustrates the key model parameters that determine the sickling of RBCs. Global sensitivity analysis illustrates the.

Fig. 2 NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ clean air policy. NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ.

Fig. 1 Size fractions of MPPs in different fertilizers.

Fig. 2 Sources of plastic waste imports into China in 2016 and cumulative plastic waste export tonnage (in million MT) in 1988–2016. Sources of plastic.

Fig. 4 Relationships between light and economic parameters.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Fig. 5 Skull 1: Tentative reconstruction.

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 3 Earthquake seismic waves detected in Berkeley.

Multiplexed four- and eight-channel devices for rapid processing

Fig. 2 Mean field results. Mean field results. (A) Solutions P(x) to Eq. 4 for a range of T and wc = (B) Modulus ∣pk∣ of order parameters versus.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

Fig. 2 Supraballs and films from binary SPs.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 3 High-tide flood extent at water levels of 1. 73, 2. 03, 2

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

The combined signal spectra of PSD for protons and helium nuclei

Fig. 1 Blood nicotine levels after escalation of nicotine intake.

Fig. 4 Effects of individual picosecond and microsecond pulses.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 6 Schematic illustration of the decreased conformational stability in the N92I mutant and its activation mechanism. Schematic illustration of the.

Fig. 2 Direct and indirect effects of richness, total abundance, and evenness on ecosystem services. Direct and indirect effects of richness, total abundance,

ZCWPW1 is needed for maintaining fertility in a sex-dependent manner

Fig. 4 Orthosteric ligand-binding pocket in CysLT1R.

Fig. 6 The knockout of Zcwpw1 leads to POI.

Fig. 1 Completely derived from natural wood, nanowood with hierarchically aligned cellulose nanofibrils can be used as an anisotropic super thermal insulator.

Fig. 3 Spatial distribution of the shoot density (high densities are represented in dark green and low ones in bright yellow) in a simulation of a P. oceanica.

Presentation transcript:

Fig. 1 ZCWPW1 expression and dynamic localization in meiotic germ cells. ZCWPW1 expression and dynamic localization in meiotic germ cells. (A) Western blotting of ZCWPW1 in isolated male germ cells, demonstrating that the Zcwpw1 expression level increased from the leptotene stage to the round spermatid stage and then disappeared in the elongated spermatid. β-Actin was used as the control. (B) Western blotting of ZCWPW1 in the cytoplasmic and nuclear fractions of PD35 wild-type testes shows that ZCWPW1 was only expressed in the nuclei. Lamin B1 was used as the marker of nuclear fractions. (C to K) Chromosome spreads of spermatocytes from the testes of PD35 Zcwpw1+/+ and Zcwpw1−/− males immunostained for ZCWPW1 (green) and SYCP3 (red). ZCWPW1 was diffuse (arrows) from the leptotene to zygotene stages (C to F, arrows). In pachytene cells, ZCWPW1 was localized in the XY body (G and H, white dashed circles). (I to K) In Zcwpw1−/− spermatocytes, no ZCWPW1 signal was detected. (L to T) Chromosome spreads of oocytes from E17.5 Zcwpw1+/+ and Zcwpw1−/− ovaries immunostained for ZCWPW1 (green) and SYCP3 (red). ZCWPW1 was diffuse (arrows) from the leptotene to pachytene stages (L to Q, arrows). (R to T) In Zcwpw1−/− oocytes, no ZCWPW1 signal was detected. Miao Li et al. Sci Adv 2019;5:eaax1101 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).