(Top) A urine sodium concentration (UNa) of approximately 30 mEq/L is observed frequently in patients with hyponatremia secondary to syndrome of inappropriate.

Slides:



Advertisements
Similar presentations
HYPONATREMIA & HYPERNATREMIA
Advertisements

Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Daniel Stairs, CRNA, MSN, MBA Excela Health School of Anesthesia.
SIADH Alexander Usorov, MD July 31, SIADH Most frequent cause of hyponatremia First described by Schwartz et al in 1957 in 2 pts with bronchogenic.
SIADH Monton 1 กค 48. Hyponatremia Hyponatremia exclude pseudohyponatremia exclude pseudohyponatremia volume status volume status Hypovolemia Euvolemia.
Beer Drinker's Potomania
Renal Clearance The renal clearance of a substance is the volume of plasma that is completely cleared of the substance by the kidneys per unit time.
Adalyn Almora Questions 3 and 4
HYPONATREMIA. What is the Osmolality? Osmolality Normal High Low Hypertonic HypoNa+ Causes an osmotic shift of water out of cells ↑ glucose Mannitol use.
RENAL Dr; bashardoust.
WEM1 Lab diagnostics MK, JSC 2015/2016. Sodium deficit Postoperatively a 70-kg patient has a serum sodium value of 120 mEq/L (120 mmol/L) to increase.
HYPONATREMIA Dr. M. A. SOFI MD; FRCP (London); FRCPEdin; FRCSEdin.
3. Compute for the plasma osmolality and the effective plasma osmolality. What is the importance of computing for such?
SIADH vs Psychogenic Polydipsia
Diabetes Insipidus and SIADH Charnelle Lee RN, MSN.
Joseph G. Verbalis, MD, Steven R
Volume 349, Issue 9047, Pages (January 1997)
Evaluation of current clinical algorithms to identify SIADH as a cause of hyponatremia in geriatric patients: A 2 year prospective study P. Ioannou1,
Dr. M. A. SOFI MD; FRCP (London); FRCPEdin; FRCSEdin
Volume 79, Pages S3-S8 (April 2011)
Severe Hypernatremia Following Treatment of the Syndrome of Inappropriate Antidiuretic Hormone Secretion  Khaldoun Soudan, MD, Wajeh Qunibi, MD  The American.
Are Sodium Transporters in Urinary Exosomes Reliable Markers of Tubular Sodium Reabsorption in Hypertensive Patients? Nephron Physiol 2010;114:p25–p34.
Dr. M. A. SOFI MD; FRCP (London); FRCPEdin; FRCSEdin
Relationship between serum sodium after racing and the weight change (in %) during exercise in 2135 athletes who competed in endurance events. •, asymptomatic.
Dr. M. A. SOFI MD; FRCP (London); FRCPEdin; FRCSEdin
Joseph G. Verbalis, MD, Steven R
Adjusted all-cause mortality risk by dialysate sodium (DNa) and predialysis serum sodium (SNa). Adjusted all-cause mortality risk by dialysate sodium (DNa)
Urinary System Day 4.
Volume 88, Issue 1, Pages (July 2015)
Relationship between urinary TNF-α and RANTES excretion
Benoit Renneboog, MD, Wim Musch, MD, Xavier Vandemergel, MD, Mario U
Joseph G. Verbalis, MD, Steven R
Pharmacokinetics and pharmacodynamics of oral tolvaptan in patients with varying degrees of renal function  Susan E. Shoaf, Patricia Bricmont, Suresh.
Pathophysiology and Management of Preeclampsia-Associated Severe Hyponatremia  Gagangeet Sandhu, MD, Senthil Ramaiyah, MD, Germaine Chan, MD, Ira Meisels,
Volume 79, Pages S3-S8 (April 2011)
Clinical Scenario 74-year-old man p/w recent gastroenteritis characterized by n/v/d x 5 days, in addition to fatigue and headache. CT head (-) in ED.
Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure  Christos P. Carvounis, Sabeeha Nisar, Samerah Guro-Razuman 
Rapidity of Correction of Hyponatremia Due to Syndrome of Inappropriate Secretion of Antidiuretic Hormone Following Tolvaptan  Jesse H. Morris, Nicole.
Renal salt wasting without cerebral disease: Diagnostic value of urate determinations in hyponatremia  J.K. Maesaka, N. Miyawaki, T. Palaia, S. Fishbane,
Is it cerebral or renal salt wasting?
Use of Desmopressin in Hyponatremia: Foe and Friend
Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion  Joseph G. Verbalis, MD, Arthur Greenberg, MD, Volker Burst, MD, Jean-Philippe.
Parathyroid hormone (PTH) levels by Dialysis Outcomes and Practice Patterns Study (DOPPS) phase and selected patient characteristics. Parathyroid hormone.
Volume 78, Issue 5, Pages (September 2010)
(A) Mean (SD) serum continuous erythropoietin receptor activator (C. E
Adjusted means (±SD) of eGFR in relation to the histologic severity of nonalcoholic steatohepatitis (i.e., NASH/fibrosis stage increasing from 0 to 3)
Renal blood flow in experimental septic acute renal failure
Lifestyle intervention was associated with improved cardiorespiratory fitness. Lifestyle intervention was associated with improved cardiorespiratory fitness.
Renal bicarbonate handling and associated diagnostic values in RTA
Ionized-to-total magnesium (Mg) and calcium (Ca) ratios are lower in patients on hemodialysis than those in patients not on dialysis. Ionized-to-total.
Ratio of actual to expected rise in sodium as calculated using the Adrogué-Madias formula. Ratio of actual to expected rise in sodium as calculated using.
Ca2+ infusion rates during all three protocol versions.
Rates of plasma sodium concentration increase before and after DDAVP administration. Rates of plasma sodium concentration increase before and after DDAVP.
Six-month change in proteinuria predicts risk for ESRD
(Left) Relationship between plasma urea and age (top; y = x ; r = 0
Plasma concentration and urinary excretion of N-terminal proatrial natriuretic peptides in patients with kidney diseases  Martina Franz, Wolfgang Woloszczuk,
Mild chronic hyponatremia is associated with gait disturbances.
In a cohort of chronically hyponatremic patients with serum sodium concentrations ≤105 mEq/L, post-therapeutic (post-Rx) neurological complications occurred.
Relationship between excess fluid, as determined by the difference between measured and estimated body water, and plasma albumin (R = −0.40, P = 0.011).
Among three residual kidney function (RKF) indices, only residual urine volume (UV) indicated an independent prognostic value in patients with UV≥0.1 or.
Pharmacokinetics and pharmacodynamics of diuretic action.
Relationships between fractional excretion of Na (FENa) and FE of urea (FEurea) in 20 patients with SIADH (•) and 15 SD patients (○) with U/P creat
Analysis of secreted proteins in the discovery panel.
Causal diagrams that represent three possible relationships between smoking, ESRD, and albumin-to-creatinine ratio (ACR) in the Study of Heart and Renal.
Distribution of SDS for serum creatinine, serum BUN, SBP, and DBP per quintiles of KS. Quintiles are expressed in SDS (see Figure 1B): 1st quintile,
Limits for safe correction are difficult to define when the serum sodium concentration is extremely low. Limits for safe correction are difficult to define.
Dosage-response gradient for colorectal cancer according to serum 25-hydroxyvitamin D [25(OH)D] concentration of five studies combined. Dosage-response.
Renal hemodynamics. Renal hemodynamics. GFR (A), effective renal plasma flow (ERPF; B), and filtration fraction (FF; C) in patients with diabetes and with.
Significant correlation between the initial urine osmolality (Uosm T0) and the variation in plasma sodium (DPNa) after 2 L of isotonic saline in 17 patients.
Survival among hemodialysis patients by geographic region in DOPPS 3 (2005–2008), with and without adjustments for patient mix differences. Survival among.
Effect of urine electrolyte concentration on serum sodium level in hypotonic hyponatremia. Effect of urine electrolyte concentration on serum sodium level.
Presentation transcript:

(Top) A urine sodium concentration (UNa) of approximately 30 mEq/L is observed frequently in patients with hyponatremia secondary to syndrome of inappropriate secretion of antidiuretic hormone (SIADH; •) or to salt depletion (SD; ○). (Top) A urine sodium concentration (UNa) of approximately 30 mEq/L is observed frequently in patients with hyponatremia secondary to syndrome of inappropriate secretion of antidiuretic hormone (SIADH; •) or to salt depletion (SD; ○). (B) All of the patients with SD presented a fractional excretion of Na (FENa) <0.5%, but low values are also observed in SIADH when the urinary flow is low (urinary/plasma creatinine ratio [U/P creat] >140). Data from reference (33), with permission from S. Karger AG. Guy Decaux, and Wim Musch CJASN 2008;3:1175-1184 ©2008 by American Society of Nephrology