Heat map of genes for which CR significantly altered expression versus AL. Cluster analysis of genes significantly changed by the CR intervention compared.

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Heat map of genes for which CR significantly altered expression versus AL. Cluster analysis of genes significantly changed by the CR intervention compared with AL (P ≤ 0.005, fold change, ≥1.5) was performed as described in Materials and Methods. Heat map of genes for which CR significantly altered expression versus AL. Cluster analysis of genes significantly changed by the CR intervention compared with AL (P ≤ 0.005, fold change, ≥1.5) was performed as described in Materials and Methods. Findings are depicted as a heat map; red, upregulated genes; green, downregulated genes. Columns, different treatment groups; rows, different genes. Changes for all treatment groups are shown for the genes for which CR compared with AL significantly changed expression, including those treatments that did not achieve statistical significance versus AL. Michela Padovani et al. Cancer Prev Res 2009;2:1076-1087 ©2009 by American Association for Cancer Research