Potential beneficial cellular pleotropic effects of DPP-4 inhibitors. Potential beneficial cellular pleotropic effects of DPP-4 inhibitors. Antithrombotic, anti-inflammatory, and atheroprotective effects are key players in the CV arena. *Makdissi A, Ghanim H, Vora M, Green K, Abuaysheh S, Chaudhuri A, Dhindsa S, Dandona P: Sitagliptin exerts an antinflammatory action. J Clin Endocrinol Metab 97:3333–3341, 2012. Vani P. Sanon et al. Clin Diabetes 2014;32:121-126 ©2014 by American Diabetes Association