Acanthosis nigricans in a patient with sarcoma of unknown origin

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Presentation transcript:

Acanthosis nigricans in a patient with sarcoma of unknown origin Kay Dietmar Brantsch, MD, Matthias Moehrle, MD Journal of the American Academy of Dermatology Volume 62, Issue 3, Pages 527-528 (March 2010) DOI: 10.1016/j.jaad.2009.02.010 Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Right axilla showing acanthosis nigricans and a subcutaneous mass. Journal of the American Academy of Dermatology 2010 62, 527-528DOI: (10.1016/j.jaad.2009.02.010) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Tumor specimen after extirpation from the right axilla. Journal of the American Academy of Dermatology 2010 62, 527-528DOI: (10.1016/j.jaad.2009.02.010) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Skin biopsy showing acanthosis, papillomatosis, hyperkeratosis, and increased dermal pigmentation. (Hematoxylin–eosin stain; original magnification: ×20.) Journal of the American Academy of Dermatology 2010 62, 527-528DOI: (10.1016/j.jaad.2009.02.010) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Histology of the axillary tumor showing proliferating cells, hyperchromatic, polymorphic nuclei, an altered cytoplasm to nucleus ratio, and many prominent eosinophilic nucleoli. (Hematoxylin–eosin stain; original magnification: ×200.) Journal of the American Academy of Dermatology 2010 62, 527-528DOI: (10.1016/j.jaad.2009.02.010) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions