Static pressure-volume curve from a patient with ARDS showing the lower inflection point (LIP) on the inflation limb signifying the beginning of significant lung recruitment and the point of maximum curvature (PMC) on the deflation limb that is believed to represent the beginning of de-recruitment (A). Static pressure-volume curve from a patient with ARDS showing the lower inflection point (LIP) on the inflation limb signifying the beginning of significant lung recruitment and the point of maximum curvature (PMC) on the deflation limb that is believed to represent the beginning of de-recruitment (A). Steeper portions of curve on each limb represent higher compliance, whereas flatter portions signify lower compliance. Panel B illustrates the impact of setting PEEP according to the LIP (following a recruitment maneuver) on end-expiratory lung volume. This has been proposed as an alternative method of adjusting PEEP that may reduce shear stress while reducing the risk of stretch-related injury compared with setting PEEP according to the PMC. See text for details. From Reference 77, with permission. Richard H Kallet Respir Care 2016;61:876-890 (c) 2012 by Daedalus Enterprises, Inc.