Maria R. Costanzo et al. JCHF 2016;4:333-344 Impact of Baseline PA Diastolic Pressure on Diuretic Changes Shown on the primary y-axis to the left are the average number of diuretic changes per patient at each baseline PA diastolic pressure (x-axis) between the PA pressure-guided HF management (solid red line) and standard of care HF management (solid blue line) groups. Poisson regression estimates of the number of diuretic changes per patient are depicted with dotted lines for each group. The cumulative sum of the total number of diuretic changes with increasing PA diastolic pressure are displayed on the secondary y-axis to the right using shaded areas. Abbreviations as in Figures 1 and 2. Maria R. Costanzo et al. JCHF 2016;4:333-344 American College of Cardiology Foundation