Prevention of radial artery graft vasospasm after coronary bypass

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Presentation transcript:

Prevention of radial artery graft vasospasm after coronary bypass Jyotirmay Chanda, MD, Igor Brichkov, BS, Charles C Canver, MD The Annals of Thoracic Surgery Volume 70, Issue 6, Pages 2070-2074 (December 2000) DOI: 10.1016/S0003-4975(00)02001-4

Fig 1 Concentration-contraction curves of radial artery to endothelin (ET-1), angiotensin II (AII), 5-hydroxytryptamine (5-HT), and norepinephrine (NE). The Annals of Thoracic Surgery 2000 70, 2070-2074DOI: (10.1016/S0003-4975(00)02001-4)

Fig 2 Vasodilatory effect of 10−5 M nifedipine (Nif) alone, 10−5 M diltiazem (Dil) alone, 10−5 M verapamil (Vp) alone, 10−5 M NTG (NTG5) alone, 10−6 M NTG (NTG6) alone, and 10−6 M NTG in combination with 10−5 M diltiazem (Dil+NTG), 10−5 M nifedipine (Nif+NTG), and 10−5 M verapamil (Vp+NTG) in endothelin-1 (ET-1)-, angiotensin II (AII)-, 5-hydroxytryptamine (5-HT)-, and norepinephrine (NE)-precontracted radial artery segments. The Annals of Thoracic Surgery 2000 70, 2070-2074DOI: (10.1016/S0003-4975(00)02001-4)