CNDT2.5 cells express mRNA for synaptophysin and neuron-specific enolase. CNDT2.5 cells express mRNA for synaptophysin and neuron-specific enolase. RT-PCR of CNDT2.5 cells in culture revealed expression of mRNA for the neuroendocrine markers synaptophysin (Syn) and neuron-specific enolase (NSE) but not chromogranin A (CgA). BON pancreatic NET cells served as a positive control for all three markers. George Van Buren II et al. Clin Cancer Res 2007;13:4704-4712 ©2007 by American Association for Cancer Research