Minimum-spanning-tree analysis of 59 C

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Minimum-spanning-tree analysis of 59 C Minimum-spanning-tree analysis of 59 C. difficile ribotype 027 isolates from 27 different regions of 14 countries typed by MLVA. Each circle (colored coded by country of origin [see key]) represents either a unique isolate or more isolates that are 100% homologous. Minimum-spanning-tree analysis of 59 C. difficile ribotype 027 isolates from 27 different regions of 14 countries typed by MLVA. Each circle (colored coded by country of origin [see key]) represents either a unique isolate or more isolates that are 100% homologous. The Dutch strains (green circles) (n = 17) are labeled by the submitting hospital plus a number. The other isolates are labeled by country and a number. The numbers between the circles represent the STRDs between MLVA types. The different-colored lines between the circles are indicative of one (green), two (red), three (blue), or four (gray) locus variants. Clindamycin-resistant isolates (n = 9) are IRE1, IRE5, IRE6, IRE8, IRE9, IRE10, FR1, BEL4, and BEL5. (Courtesy of National Reference Laboratory, Leiden, Netherlands; created by Celine Harmanus and used with permission.)‏ J. Freeman et al. Clin. Microbiol. Rev. 2010; doi:10.1128/CMR.00082-09