Patient 1: 3½-year-old boy with leukokoria, posterior synechiae, and total retinal detachment. Patient 1: 3½-year-old boy with leukokoria, posterior synechiae,

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Patient 1: 3½-year-old boy with leukokoria, posterior synechiae, and total retinal detachment. Patient 1: 3½-year-old boy with leukokoria, posterior synechiae, and total retinal detachment. A, Sonogram shows detachment and thickening of the retina (arrow).B, Contrast-enhanced CT scan shows crescent-shaped hyperdensity of the posterior pole due to retinal detachment (arrow), with no calcification.C and D, Unenhanced (C) and enhanced (D) T1-weighted MR images show retinal detachment containing material with a high signal intensity (arrow, C) and moderate enhancement of the zone of detachment.E, T2-weighted MR image shows an irregularly thickened, detached retina (arrow).F and G, Low- (F) and high-power (G) histologic sections show retinoblastoma with an infiltrating component (arrows, G) destroying the retinal architecture (arrowheads, G) and an exophytic component (arrow, F) in the temporal zone of detachment (hematein-eosin-saffron stain, original magnifications ×2 and ×25, respectively). (Box in F denotes magnified area in G.)‏ Hervé J. Brisse et al. AJNR Am J Neuroradiol 2001;22:499-504 ©2001 by American Society of Neuroradiology