AXL is not expressed in human prostate tumors.

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Histogenic analysis confirms prostate cancer metastasis to lung.

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AXL is not expressed in human prostate tumors. AXL is not expressed in human prostate tumors. A, AXL expression in prostate cancer patients who did and did not experience a biochemical recurrence (n = 1,405 patients, GenomeDx GRID data set). P value was calculated using the Wilcoxon rank test. B, Recurrence-free survival of patients with high (above the median) and low (below the median) AXL expression (n = 571 patients, Taylor et al. 2010; visualized and analyzed with Project Betastasis). C, Representative images of AXL IHC staining of a prostate tissue microarray; LN, lymph node. C42B cells served as a negative control and DU145 as a positive control. All images at original magnification ×200. D, AXL IHC staining in metastatic patient tissue; top: scale bar, 100 μm; bottom: scale bar, 50 μm. Haley D. Axelrod et al. Mol Cancer Res 2019;17:356-369 ©2019 by American Association for Cancer Research