Downregulation of ROCK signaling in striatal tissues from SA/SA mutant mice. Downregulation of ROCK signaling in striatal tissues from SA/SA mutant mice.

Slides:

Advertisements

Similar presentations

Volume 114, Issue 5, Pages (May 1998)

Advertisements

Volume 133, Issue 1, Pages (July 2007)

Volume 68, Issue 4, Pages (October 2005)

From: IGF-1 Regulates the Extracellular Level of Active MMP-2 and Promotes Müller Glial Cell Motility Invest. Ophthalmol. Vis. Sci ;56(11):

p < Figure S1 p55 viral protein level Relative HIV-1

MicroRNAs Involved in the Mitogen-Activated Protein Kinase Cascades Pathway During Glucose-Induced Cardiomyocyte Hypertrophy E. Shen, Xuehong Diao, Xiaoxia.

Volume 19, Issue 6, Pages (June 2014)

A Signal Transduction Pathway from TGF-β1 to SKP2 via Akt1 and c-Myc and its Correlation with Progression in Human Melanoma Xuan Qu, Liangliang Shen,

Expression of phosphorylated BNP, HIF-2 alpha and beta actin proteins in the primary tumour tissues using western blotting. Expression of phosphorylated.

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia by Hironori.

Jaya Sahni, Andrew M. Scharenberg Cell Metabolism

Antiproliferative effects of erlotinib correlate poorly with abundance of p-EGFR. Antiproliferative effects of erlotinib correlate poorly with abundance.

Volume 133, Issue 1, Pages (July 2007)

Phosphorylation of EL1 on SLR1 is crucial for GA signalling.

C D Coomassie stained gel PD:RNF4 KDa KDa

Partial knockdown of MPST markedly ameliorates hepatic steatosis in vivo. Partial knockdown of MPST markedly ameliorates hepatic steatosis in vivo. (A–C)

DH E2 infusion significantly increased phosphorylation of the p42 isoform of ERK (A) and of Akt (B) in the DH of OVX females, but not sham GDX males. DH.

S534 phosphorylation affects DNA binding and gene expression by NF-κB at late time points through regulation of p65 stability. S534 phosphorylation affects.

The ΔrlmA mutant strain has impaired CWI pathway activation.

Histamine Contributes to Tissue Remodeling via Periostin Expression

Supplement Figure 2 HEK 293 cells

Cocaine exposure downregulates miR-125b expression.

Volume 68, Issue 4, Pages (October 2005)

Anne T. Funding, Claus Johansen, Matthias Gaestel, Bo M

Xenon preconditioning differently regulates p44/42 MAPK (ERK 1/2) and p46/54 MAPK (JNK 1/2 and 3) in vivo† N.C. Weber, J. Stursberg, N.M. Wirthle, O.

Distribution of the phosphoproteins based on GO analysis, including biological process (Left) and cellular component (Right). Distribution of the phosphoproteins.

Essential Role of TGF-β Signaling in Glucose-Induced Cell Hypertrophy

Analysis of GFP expression in gfp loss-of-function mutants.

Leila Khamzina, Philip A Gruppuso, Jack R Wands Gastroenterology

Volume 54, Pages S189-S191 (September 1998)

Altered development of small-worldness in pcdh19 mutants.

Developmental changes in transitivity in pcdh19 mutants.

Development of assortativity in wild-type and pcdh19 mutant larvae.

Fig. 2. Histone H3 phosphorylation appears at prometaphase upon C4 treatment.(A) Western blots were realized on cells synchronized at mitotic entry in.

Biochemical properties and expression profile of KCC2-pHext and its mutants with truncated N and C termini. Biochemical properties and expression profile.

Oral administration of CX-4945 suppresses Tau phosphorylation in DYRK1A-overexpressing mice. Oral administration of CX-4945 suppresses Tau phosphorylation.

Effects of canagliflozin on AMPK, lipid synthesis, and fatty acid oxidation in intact cells. Effects of canagliflozin on AMPK, lipid synthesis, and fatty.

Loss of Keratin 10 Leads to Mitogen-activated Protein Kinase (MAPK) Activation, Increased Keratinocyte Turnover, and Decreased Tumor Formation in Mice

Conversion of proBDNF to mature BDNF occurs after the first pairing session of conditioning as shown by Western blot analysis. Conversion of proBDNF to.

CK2 phosphorylates mammalian FMRP S499.

Plasma ethanol levels assayed 1 and 3 h after WT/WT and SA/SA (left) or SD/SD (right) mice were injected with ethanol (3 g/kg). Plasma ethanol levels assayed.

APT1 palmitoylation and localization.

Disruption of MAM integrity and insulin signaling in liver of diet-induced diabetic mice. Disruption of MAM integrity and insulin signaling in liver of.

Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple time points. Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple.

Increased proIGF-II and decreased IGF-IIR in BTBR compared with B6 mice. Increased proIGF-II and decreased IGF-IIR in BTBR compared with B6 mice. Western.

Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation.

Log10-transformed EEG power in the 0- to 30-Hz range measured in females (white) and males (gray) at each channel for NFB (left) and CAL (right), shown.

(A) qRT-PCR-analysis of P450 aromatase mRNA in brains from control and d-Asp-treated frogs. (A) qRT-PCR-analysis of P450 aromatase mRNA in brains from.

Kinetics of BDNF-induced Erk, Akt and PLCγ activation in the presence of 15 mM NaCl or 15 mM KCl. Representative western blots (A) and quantitative plots.

Electrically evoked dopamine transients and regulation of dopamine signals by firing frequency in wild-type and triple-synuclein-null mutant mice measured.

OTX2 in RMS and V-SVZ is non-cell-autonomous.

CML-HSA treatment activates MAPK family members ERK1/2 and p38 but not JNK. Samples were taken at the indicated times after 100 μg/ml CML-HSA exposure.

Insulin resistance and hepatic steatosis in ASKO mice.

Autophagy protein abundance, but not autophagy flux, is altered in Cnot3-depleted heart. Autophagy protein abundance, but not autophagy flux, is altered.

AKT thr308 phosphorylation related to total AKT2 protein in SOL muscle (m. soleus) (A) and EDL muscle (m. extensor digitorum longus) (D) and AKT ser472.

Aβ-mediated Ras-MAPK signaling and Cyclin D1 expression in B103 cells are dependent on APP expression and can be reversed with MEK or Ras inhibition. Aβ-mediated.

No difference in the properties of mEPSCs of DGCs recorded in brain slices obtained from PBS-injected (control) and TMEV-infected mice during the acute.

MSK1 is necessary for BDNF-dependent CREB phosphorylation in area CA1.

NCS-Rapgef2-dependent ERK activation in mouse NAc following D1 dopamine receptor agonist SKF and psychostimulants D-amphetamine or cocaine administration.

Western blotting for GluR1.

The alterations of GSK-3 activity after pharmacological manipulation.

Western blot analysis using tissues of the striatum and colchicine-treated retina. Western blot analysis using tissues of the striatum and colchicine-treated.

Power spectra of EMG during the pre- and post-feedback sessions.

Time-dependent changes in caspase-3 during reperfusion after 2 hr middle cerebral artery occlusion. Time-dependent changes in caspase-3 during reperfusion.

A, The ratio of currents elicited by an EC50 concentration of ACh and 100 µm menthol over the current elicited by ACh alone. A, The ratio of currents elicited.

Dysregulated NF-κB activation in Il1r8+/+/lpr and Il1r8−/−/lpr mice.

Expression of dominant-negative RasN17 completely suppresses Ras activation in Rh1 cells. Expression of dominant-negative RasN17 completely suppresses.

by Dana S. Levy, Jason A. Kahana, and Rakesh Kumar

Effects of UVB on AKT in SKH-1 mouse epidermis.

Volume 12, Issue 6, Pages (March 2002)

Presentation transcript:

Downregulation of ROCK signaling in striatal tissues from SA/SA mutant mice. Downregulation of ROCK signaling in striatal tissues from SA/SA mutant mice. A, ROCK activity levels in the striatal tissues of SA/SA (left) and SD/SD (right) mutant mice measured by immunoassays. B, ROCK protein levels in striatal tissues from SA/SA (left) and SD/SD (right) mutant mice measured by Western blotting (upper). ROCK protein level (A.U.) in each tissue was normalized to that of β-tubulin (Tub, lower). C, ROCK kinase activity (mU) per milligram of striatal tissues and normalized to ROCK protein amount (bottom) in SA/SA (left) and SD/SD (right) mutant mice. Scatter diagrams of the two variables are shown in upper panels. D, Phosphorylation of 60-kDa Akt at Ser473 (P-Akt) in the striatal tissues of SA/SA mutant mice as measured by Western blotting. Akt phosphorylation levels were normalized to the level of total Akt. Data are mean ± SD; *p < 0.05, **p < 0.01 by unpaired two-tailed Welch’s t tests. Goro Kato eNeuro 2019;6:ENEURO.0418-18.2019 ©2019 by Society for Neuroscience