Alessandro Fiocchi, MD, Holger J

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Presentation transcript:

Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA): A summary report Alessandro Fiocchi, MD, Holger J. Schünemann, MD, PhD, Jan Brozek, MD, Patrizia Restani, PhD, Kirsten Beyer, MD, Riccardo Troncone, MD, Alberto Martelli, MD, Luigi Terracciano, MD, Sami L. Bahna, MD, Fabienne Rancé, MD, Motohiro Ebisawa, MD, Ralf G. Heine, MD, FRACP, Amal Assa'ad, MD, Hugh Sampson, MD, Elvira Verduci, MD, G.R. Bouygue, MSc, Carlos Baena-Cagnani, MD, Walter Canonica, MD, Richard F. Lockey, MD Journal of Allergy and Clinical Immunology Volume 126, Issue 6, Pages 1119-1128.e12 (December 2010) DOI: 10.1016/j.jaci.2010.10.011 Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

SDS-PAGE of cow's milk. ALA, Bovine α-lactalbumin; α-cas, bovine α-casein; β-cas, bovine β-casein; BLG, bovine β-lactoglobulin; Hcas, Human casein; HLA, human lactalbumin; Lfe, human lactoferrin. Journal of Allergy and Clinical Immunology 2010 126, 1119-1128.e12DOI: (10.1016/j.jaci.2010.10.011) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Self/parental report of CMA stratified by age Self/parental report of CMA stratified by age. P values connote the level of heterogeneity by age group and in total. Journal of Allergy and Clinical Immunology 2010 126, 1119-1128.e12DOI: (10.1016/j.jaci.2010.10.011) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Prevalence of symptoms and sensitization (tested by means of SPTs or IgE antibody assays) and stratification by age. P values connote the level of heterogeneity by age group and in total. N/A, Not applicable. Journal of Allergy and Clinical Immunology 2010 126, 1119-1128.e12DOI: (10.1016/j.jaci.2010.10.011) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions