A PIP Gets the Plasmodium Protein Export Pathway Going

Slides:



Advertisements
Similar presentations
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Advertisements

Human Gut Microbes Use Multiple Transporters to Distinguish Vitamin B12 Analogs and Compete in the Gut Patrick H. Degnan, Natasha A. Barry, Kenny C. Mok,
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,
Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.
Genes Induced Late in Infection Increase Fitness of Vibrio cholerae after Release into the Environment Stefan Schild, Rita Tamayo, Eric J. Nelson, Firdausi.
Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells Wang Nguitragool, Abdullah A.B. Bokhari, Ajay D. Pillai,
A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.
Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,
Fungal Sex Receptors Recalibrated to Detect Host Plants
RAS and ROS—A Story of Pseudomonas Survival
Trained Immunity: An Ancient Way of Remembering
Enterococcus faecalis: E. coli’s Siderophore-Inducing Sidekick
Influenza A Virus Lures Autophagic Protein LC3 to Budding Sites
Influenza Vaccines: Challenges and Solutions
Sickle Cell MicroRNAs Inhibit the Malaria Parasite
Role of the Parasite and Host Cytoskeleton in Apicomplexa Parasitism
The DNA Damage Response: Ten Years After
Jenner's Irony: Cowpox Taps into T Cell Evasion
Bacterial Reductionism: Host Thiols Enhance Virulence
Malaria Parasite Invasion: Achieving Superb Resolution
Unsweetened IgG Is Bad for Dengue Patients
Volume 18, Issue 4, Pages (October 2015)
Christopher D. Dupont, Christopher A. Hunter  Immunity 
Shigella Targets T Cells
Octavio Ramilo, Asunción Mejías  Cell Host & Microbe 
Dynamins Are Forever: MxB Inhibits HIV-1
Jonathan B. Muyskens, Karen Guillemin  Cell Host & Microbe 
Autophagy, Apoptosis, and the Influenza Virus M2 Protein
A Microbiome Foundation for the Study of Crohn’s Disease
Type VI Secretion: Not Just for Pathogenesis Anymore
The CAT(2) Comes Back Cell Host & Microbe
Exploiting Old Pathogens to Create New Therapeutics
Neural-Immune Communication in Caenorhabditis elegans
At the Intersection of Plant Growth and Immunity
Organelle Division: Dynamin-Related Proteins in Apicomplexans
Malaria Parasite Invasion: Achieving Superb Resolution
Deconstructing Export of Malaria Proteins
Finding Leishmania: A Deadly Game of Hide-and-Seek
Mycobacterial Lipid Logic
Taking Charge: Feeding Malaria via Anion Channels
Calnexin Bridges the Gap toward a Pan-Fungal Vaccine
NO Signals from the Cancer Stem Cell Niche
Volume 2, Issue 4, Pages (October 2007)
Recognizing Macrophage Activation and Host Defense
Gut Microbes Take Their Vitamins
A Feedforward Loop Links Gaucher and Parkinson's Diseases?
Membrane Trafficking in Plant Immunity
A Microbiome Foundation for the Study of Crohn’s Disease
Fighting for Resources: Who Started the Battle? Who Is Winning It?
The Yeast Saccharomyces cerevisiae: A Versatile Model System for the Identification and Characterization of Bacterial Virulence Proteins  Keri A. Siggers,
Shigella Navigates Tight Corners
Yusuke Saijo, Paul Schulze-Lefert  Cell Host & Microbe 
Bacteria Moving into Focus of Human Cancer
Wilbert Bitter, Coen Kuijl  Cell Host & Microbe 
Viral Suppressors of RNA-Based Viral Immunity: Host Targets
Plant TRAF Proteins Regulate NLR Immune Receptor Turnover
Crossing the Rubicon: New Roads Lead to Host Defense
Volume 9, Issue 6, Pages (June 2011)
The DNA Damage Response: Ten Years After
Antigen Smuggling in Tuberculosis
Michal Shapira, Alexandra Zinoviev  Cell Host & Microbe 
Plants Pack a Quiver Full of Arrows
Two Tales (Tails) of SAMHD1 Destruction by Vpx
Apicomplexan AMA1 in Host Cell Invasion: A Model at the Junction?
Understanding How Hepatitis C Virus Builds Its Unctuous Home
The Mammalian Gut as a Matchmaker
A Host MicroRNA Brokers Truce with HSV-1
Jenner's Irony: Cowpox Taps into T Cell Evasion
HIV and Chemokine Binding to Red Blood Cells—DARC Matters
The Tangled Web of Signaling in Innate Immunity
Presentation transcript:

A PIP Gets the Plasmodium Protein Export Pathway Going Rays H.Y. Jiang, Matthias Marti  Cell Host & Microbe  Volume 11, Issue 2, Pages 99-100 (February 2012) DOI: 10.1016/j.chom.2012.01.011 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 PI(3)P Functions in Plasmodium and Phytophthora In the apicomplexan Plasmodium, parasite PI(3)P is involved in protein secretion from the ER to the host cell, in hemoglobin uptake from the host cell into the parasite food vacuole, and probably in apicoplast function. In the oomycete pathogen Phytophthora, host PI(3)P is required for protein translocation into the host cell. The red circle represents the Plasmodium-infected RBC, and the green square represents the oomycete-infected plant cell. The arrows indicate the direction of trafficking events. AP: Aicoplast; ER: endoplasmic reticulum; FV: food vacuole; PV: parasitophorous vacuole; RBC: red blood cell. Cell Host & Microbe 2012 11, 99-100DOI: (10.1016/j.chom.2012.01.011) Copyright © 2012 Elsevier Inc. Terms and Conditions