A Case of Cryptogenic Dyspnea: Disseminated Cryptococcosis

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Presentation transcript:

A Case of Cryptogenic Dyspnea: Disseminated Cryptococcosis Brett W. Sperry, MD, Edward W. Howard, MBChB(Hons), PhD, Steven Gitterman, MD, Julio A. Panza, MD The American Journal of Medicine Volume 127, Issue 8, Pages 707-710 (August 2014) DOI: 10.1016/j.amjmed.2014.04.007 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Electrocardiography showed sinus tachycardia with nonspecific T wave inversions, an S wave in lead I, and a small Q wave in lead III. The American Journal of Medicine 2014 127, 707-710DOI: (10.1016/j.amjmed.2014.04.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 2 A chest radiograph revealed prominent pulmonary vasculature. The American Journal of Medicine 2014 127, 707-710DOI: (10.1016/j.amjmed.2014.04.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 3 Transthoracic echocardiography in the parasternal short-axis view disclosed right ventricular dilatation and a flattened intraventricular “D-shaped” septum consistent with right ventricular pressure overload. The American Journal of Medicine 2014 127, 707-710DOI: (10.1016/j.amjmed.2014.04.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 4 A hematoxylin and eosin stain of the lung parenchyma showed cryptococcal infection with intra-alveolar involvement (arrowhead) and capillary occlusions (arrow). The American Journal of Medicine 2014 127, 707-710DOI: (10.1016/j.amjmed.2014.04.007) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 5 Cryptococcal organisms in myocardial capillaries (arrow) as well as an intramyocardial cryptococcoma (arrowhead) were visible in another hematoxylin and eosin stain. The American Journal of Medicine 2014 127, 707-710DOI: (10.1016/j.amjmed.2014.04.007) Copyright © 2014 Elsevier Inc. Terms and Conditions