Risk (aOR) of breast cancer associated with the combination of putative at-risk genotypes of the MRN genes and the reproductive risk factors of a history.

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Risk (aOR) of breast cancer associated with the combination of putative at-risk genotypes of the MRN genes and the reproductive risk factors of a history of pregnancy, age at first FTP, or number of FTP. The aOR of breast cancer development associated with ... Risk (aOR) of breast cancer associated with the combination of putative at-risk genotypes of the MRN genes and the reproductive risk factors of a history of pregnancy, age at first FTP, or number of FTP. The aOR of breast cancer development associated with the combination of the number of putative high-risk genotypes and reproductive risk factors was estimated in a multivariate logistic regression model containing age, a family history of breast cancer, body mass index, and a group of dummy variables to represent the four different combinations of genes (number of putative high-risk genotypes) and reproductive risk factor status. Nulliparous women were not included in the analysis of the combined effect on cancer risk of the number of high-risk genotypes and age at first FTP. Huan-Ming Hsu et al. Cancer Epidemiol Biomarkers Prev 2007;16:2024-2032 ©2007 by American Association for Cancer Research