Differentiation of glioma stem cells.

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Copyright © 2015 by the American Osteopathic Association.

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Imatinib mesylate inhibits collagen synthesis in human breast stromal fibroblasts. Imatinib mesylate inhibits collagen synthesis in human breast stromal.

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Presentation transcript:

Differentiation of glioma stem cells. Differentiation of glioma stem cells. Morphology of stem (COMI; DEMI; top) and nonstem (D54; U373; bottom) glioma cell lines. Cells were cultured in the presence of EGF-FGF (stem conditions) or fetal calf serum [(FCS) - differentiating conditions] for 21 days and their morphology photographed with an inverted microscope (Reprinted by permission from the American Association for Cancer Research: Mol Cancer Res 7:383–92, 2009). Guido Frosina Mol Cancer Res 2009;7:989-999 ©2009 by American Association for Cancer Research