Inhibition of active sodium absorption leads to a net liquid secretion into in vivo rabbit lung at two levels of alveolar hypoxia B. Nagyova, M. O’Neill,

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Inhibition of active sodium absorption leads to a net liquid secretion into in vivo rabbit lung at two levels of alveolar hypoxia B. Nagyova, M. O’Neill, K.L. Dorrington British Journal of Anaesthesia Volume 87, Issue 6, Pages 897-904 (December 2001) DOI: 10.1093/bja/87.6.897 Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig. 1 Liquid uptake by pulmonary epithelium as a function of mixed venous oxygen tension for the liquid-filled left lung of the rabbit in four groups of six animals. Closed circles are for animals with amiloride and phloridzin (inhibitors of apical sodium transport) in the instillate; open circles are for controls. Data are liquid flows measured for the period 200–360 min after initially filling the lung with liquid. The difference between the upper and lower lines is assumed to be the absorptive contribution of active sodium transport. There are no significant differences between liquid uptakes at low and high values of P v ¯ O2. British Journal of Anaesthesia 2001 87, 897-904DOI: (10.1093/bja/87.6.897) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions