Neurological outcomes of congenital CMV infection.

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Presentation transcript:

Neurological outcomes of congenital CMV infection. Neurological outcomes of congenital CMV infection. Examples of computed tomography (A) and magnetic resonance imaging (B and C) of three infants with severe symptomatic congenital CMV infection with CNS involvement are shown. The classical pattern of injury described with congenital CMV infection involving the CNS is characterized by periventricular calcifications (panel A, arrow). Other consequences of fetal brain infection include abnormalities of neuronal migration, leading to polymicrogyria (panel B, arrows) and, in extreme cases, profound structural defects such as porencephalic cysts with associated schizencephaly (panel C, arrow). Maxim C.-J. Cheeran et al. Clin. Microbiol. Rev. 2009; doi:10.1128/CMR.00023-08