Foundational Structuring: Developing socially responsible biotechnology in a rapidly changing global environment Michael C. Johns University of Massachusetts, Boston 4/7/2010

Process analysis Denmark - Economy of stem cell innovation Negotiating with the public Multi-disciplinary approach Understanding the needed social conditions Norway – Frustrating politics and morality

Case Studies 1980 - Genetic blood disorder & consent 2007 - Rheumatoid arthritis & IRB 2009 - Juvenile diabetes & CAMR Now - Sickle cell disease Now - Cancer

Ethics Relevant questions need to put with regard to the potential medical, sociological and psychological dangers inherent in the use of genetic engineering (Suzuki & Knudson, 1989) The development of technology and contemporary civilization demand a proportionate development of morals and ethics. (Pope John Paul II, 1979)

Tensions of time and truth In the biomedical area, for example, commodification of new drugs or procedures often begin with a wedge group (Taylor 2009) I suppose it’s probably the major revolution in the whole history of our understanding of our selves (Venter & Dawkins, 2008)

Suspending time in tension, torsion & compression I suggest that structures, supports and alliances be put in place in a multi-disciplinary fashion that is inclusive sooner, of all parties that will take interest later

Foundational structuring Imagine Create Play Share Reflect Change…and repeat in a Fibonacci like upward constructive spiral

Interpretive factors Structure Relationships Mutual understandings & agreements Sharing Dialogue Change timing

Areas for Future Study Institutional review board process - analyze and evaluate effectiveness Further develop model of foundational structuring

Bipolarized Methodologies of Science & Policy Introduction to Society Fictional data - Point is to show expected potential of integrated structure over time