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© The Author(s) 2014. Published by Science and Education Publishing. Table 1. Effect of lopinavir/ritonavir, sulfamethoxazole/trimethoprim and their combination on serum potassium (mmol/l) of albino rats Dose mg/kg Week2 Week4 Week 6 Week 8 CONTROL 4.35±0.8 4.45±2.7 4.65±1.8 4.55±3.6 SMX/TMP (11.2/2.3) 4.43±3.2 4.67±0.3 4.70±3.4 5.85±5.3 LPV/r (11.4/2.9) 4.50±2.4 4.83±4.3 4.95±2.5 5.35±1.3 SMX/TMP+LPV/r 4.73±4.2 4.91±1.1 5.13±3.5 5.58±2.8 Results are express as mean ± SEM, the superscript (*) means significant difference with respect to the control at p<0.05(ANOVA). Adikwu Elias et al. Renal Effect of Lopinavir/Ritonavir and Sulfamethoxazole/Trimethoprim in Albino Rats. American Journal of Pharmacological Sciences, 2014, Vol. 2, No. 5, 77-81. doi:10.12691/ajps-2-5-1 © The Author(s) 2014. Published by Science and Education Publishing.