The future TB clinic. The future TB clinic. Sputum, saliva, and fecal samples are collected from patients for genome sequencing, SNP typing, or metagenomic.

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Presentation transcript:

The future TB clinic. The future TB clinic. Sputum, saliva, and fecal samples are collected from patients for genome sequencing, SNP typing, or metagenomic profiling to identify the presence of M. tuberculosis; provide strain identification and epidemiological information; identify genetic susceptibility to drug toxicity, drug pharmacokinetics, and susceptibility to reactivation of latent TB; and describe the patient-specific microbiome and its potential for oral drug biotransformation after digestion. Marta Wlodarska et al. Clin. Microbiol. Rev. 2015; doi:10.1128/CMR.00124-14