The I1307K APC gene variant was identified using primers designed to detect the I1307K. The I1307K APC gene variant was identified using primers designed.

Slides:



Advertisements
Similar presentations
DNA analysis on patients with STS deficiency
Advertisements

Odds ratios for change in PD from earliest mammogram within levels of earliest PD. No evidence for an interaction of earliest PD and change in PD on breast.
by S. Kangsadalampai, and P.G. Board
Volume 116, Issue 1, Pages (January 1999)
Flow diagram of the literature search and selection process in the PubMed and Scopus databases. Flow diagram of the literature search and selection process.
The APC I1307K Allele and BRCA-Associated Ovarian Cancer Risk
Genomic alterations in breast cancer cell line MDA-MB-231.
Line graph of preoperative saliva samples and cancerous tissue that were methylated at specific gene loci. Line graph of preoperative saliva samples and.
Variability in protein concentration of urine over a 10-d collection from a single healthy volunteer. Variability in protein concentration of urine over.
Genomic DNA methylation (ng mCyt/μg DNA) according to combined MTHFR 1298A>C and 677C>T genotypes and low or high plasma folate levels (i.e., below or.
Comparison of the banding patterns from randomly amplified polymorphic DNA PCR assays of sequential B pseudomallei isolates from each of the cases. Comparison.
miRNA expression patterns in stools from healthy subjects.
Tumor intrinsic subtype is reflected in cancer-adjacent tissue.
Volume 116, Issue 1, Pages (January 1999)
Screening for Expanded Alleles of the FMR1 Gene in Blood Spots from Newborn Males in a Spanish Population  Isabel Fernandez-Carvajal, Paulina Walichiewicz,
Allele-Specific, Non-Extendable Primer Blocker PCR (AS-NEPB-PCR) for DNA Mutation Detection in Cancer  Haiying Wang, John Jiang, Bianca Mostert, Anieta.
Representative RAPD profiles from pools of H
HPLC analysis of the glucosinolate composition of the broccoli sprouts (A) and placebo (C) beverages prepared from the first and fourth aqueous extracts.
Principal component analysis of adipose tissue fatty acids.
Kathleen M. Murphy, Tanya Geiger, Michael J. Hafez, James R
Clinically significant precounseling cancer distress modifies counseling method's effect on testing uptake. *, statistically significant difference observed.
Analytical Evaluation of Primer Engineered Multiplex Polymerase Chain Reaction– Restriction Fragment Length Polymorphism for Detection of Factor V Leiden.
PCR amplification of the ORF encoding the cytosolic p36 protein of M
Risk of PTC associated with serum concentrations of TSH and thyroid hormones among females, stratified by tumor size. *, Conditional logistic regression,
Brand-specific incremental lifetime cancer risk subtotals: \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts}
BRCA1 promoter methylation detected in the peripheral blood and corresponding tumor. BRCA1 promoter methylation detected in the peripheral blood and corresponding.
LD structure of the TOX3/LOC region in HapMap CEU and YRI populations.
The power to detect an OR of 2
Histopathologic characteristics in HL-mice and HL-HPS-mice.
Scatterplot and LD map of the genotyped tagging SNPs along the TOX3/LOC region. Scatterplot and LD map of the genotyped tagging SNPs along the TOX3/LOC
Meta-analysis of five prospective studies examining the associations between urinary melatonin secretion and breast cancer risk. Meta-analysis of five.
Increased levels of branching on serum glycoproteins from patients with HCC. A, focus on larger branched glycans from 4 representative cirrhotics, and.
Multivariate-adjusted breast density means for joint relation of IGF-I with IGFBP-3 in premenopausal women. Multivariate-adjusted breast density means.
Analysis of studies that examined the association between diabetes mellitus and prostate cancer. Analysis of studies that examined the association between.
Risk (aOR) of breast cancer associated with the combination of putative at-risk genotypes of the MRN genes and the reproductive risk factors of a history.
Age-adjusted breast cancer incidence rates in females by age-adjusted HD incidence rates in females 15–34 years of age in 135 populations in the world.
Constitutive characteristics in HL-mice and HL-HPS-mice.
Regional association plot of genotyped and imputed SNPs in proximity to rs , summarizing evidence of interaction with at least weekly heartburn or.
The truncating mutation c
Age-adjusted incidence and mortality rates by race for breast cancer (all ages, females, SEER 9 registries for , age adjusted to the 2000 United.
Parity explains the age-associated increase in ANA prevalence in women ages 12 to 59 years, but not in those ages 60+. Parity explains the age-associated.
A, Proportion of variants detected in the MMR genes.
Distributions of CD4, Th1, and Th2 in adults (n = 16; A) and children (n = 50; B). Distributions of CD4, Th1, and Th2 in adults (n = 16; A) and children.
Gene copy number analysis by multiplexed quantitative differential PCR for BRCA1 and BRCA2 for 23 DNA specimens obtained from patients of Hispanic ancestry.
BRCA1 del (ex 9-12) haplotype.
Detection of PSA-mRNA by single (first panel, 710 bp) and nested (second panel, 455 bp) RT-PCR. Detection of PSA-mRNA by single (first panel, 710 bp) and.
Analysis of mRNA and protein levels of Loricrin, COMP, CXCL9, KRT19, and CYP 3A5 genes in OSFs compared with normal controls. Analysis of mRNA and protein.
Categories of system-based chronic and late medical and neuropsychologic health events graded in the SJLIFE study. Categories of system-based chronic and.
Genotype analysis of transient CRISPR system transformants.
Representative photograph of somatic mutations detected by PCR-SSCP.
Methylation-specific PCR of APC, RASSF1A, and p14ARF genes in bladder tumor and urine DNAs. In the APC gel panel viewed from left to right, the first (TCC34)
Analysis of serum TIMP3, GPX3, and TIMP1.
One-way hierarchical cluster analysis of SAM-identified genes using the TMEV software to see the data substructure. One-way hierarchical cluster analysis.
Scatter plot of serum OPN levels and its correlation with patient survival. Scatter plot of serum OPN levels and its correlation with patient survival.
Association of MTR A2756G with risk of localized and advanced prostate cancer: dominant model comparing (G/G and A/G) versus A/A genotypes (I-V, inverse-variance.
DNA-binding and double-strand break formation by Vpr.
Keratinocyte-specific disruption of the Stat3 gene by the Cre-LoxP system. Keratinocyte-specific disruption of the Stat3 gene by the Cre-LoxP system. A,
GATA-3 immunostaining was scored semiquantitatively; tumors with
End joining of BstXI substrates by PCO cultures.
A, LOH on chromosome 17q (D17S785; expected size, 181–207 bp) in SC-IDC (Lane 2), SC-DCIS (Lane 3), clear-cut normal epithelial cells (Lane 4), DCIS (Lane.
A, Proportion for different in silico predictions at the RNA level.
The pattern of association between all-cancer mortality risk and long-term exposure to PM2.5 (μg/m3). The pattern of association between all-cancer mortality.
Detection of E-cadherin fragments in human prostate cancer metastases.
Individuals affected with cancer included in the Lynch syndrome are colored. Individuals affected with cancer included in the Lynch syndrome are colored.
Quantile–quantile plots of 42 interaction P values for seven SNPs under investigation. Quantile–quantile plots of 42 interaction P values for seven SNPs.
Pooled effect of exercise on glucose, IR, IGF1, and IGFBP3 in breast cancer survivors. Pooled effect of exercise on glucose, IR, IGF1, and IGFBP3 in breast.
BRCA1 protein functional domains and predicted frameshift and premature truncation. BRCA1 protein functional domains and predicted frameshift and premature.
Schematic representation of the HPV genome, highlighting the regions important in PCR-based HPV analysis. Schematic representation of the HPV genome, highlighting.
Epithelial and stromal percentage clusterin staining in normal nonadjacent colonic tissue and matched tumor tissue in 202 patients with stage II colorectal.
CONSORT diagram. a, 5 had a major treatment violation (3 refused and 2 received wrong treatment) but were included in the analyses; b, 4 had a major treatment.
Presentation transcript:

The I1307K APC gene variant was identified using primers designed to detect the I1307K. The I1307K APC gene variant was identified using primers designed to detect the I1307K. The variant fragment length is 130 bp, whereas the wild-type allele was 105 + 25 bp. MW, molecular weight; Lanes 1–5 and 7, wild type APC gene; Lane 6, I1307K APC gene variant; Lane 8, positive control; Lane 9, H2O negative control. Hana Strul et al. Cancer Epidemiol Biomarkers Prev 2003;12:1012-1015 ©2003 by American Association for Cancer Research