TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal region. TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal.

Slides:

Advertisements

Similar presentations

Invest. Ophthalmol. Vis. Sci ;44(9): doi: /iovs Figure Legend:

Advertisements

Cherie M Southwood, James Garbern, Wei Jiang, Alexander Gow Neuron

Volume 35, Issue 1, Pages (July 2002)

Volume 66, Issue 1, Pages (July 2004)

Volume 71, Issue 3, Pages (February 2007)

VAP‐A is recruited to interorganelle contact sites together with MOSPD2 VAP‐A is recruited to interorganelle contact sites together with MOSPD2 AHeLa cells.

TIE2hi/VEGFAhi TEMs are present in the TMEM

Volume 30, Issue 2, Pages (May 2001)

Marie-Thérèse Leccia Journal of Investigative Dermatology

Fig. 1. Aberrant JNK pathway activation in mouse models of ALS and in spinal cord tissue from patients with sporadic ALS. Aberrant JNK pathway activation.

Graham R. Huesmann, David F. Clayton Neuron

The Active Transport of Myelin Basic Protein into the Nucleus Suggests a Regulatory Role in Myelination Liliana Pedraza, Lazar Fidler, Susan M Staugaitis,

A Truncating Mutation of TRAPPC9 Is Associated with Autosomal-Recessive Intellectual Disability and Postnatal Microcephaly Ganeshwaran H. Mochida, Muhammad.

Detection and tracking of individual SNAP-tagged proteins on the surface of living cells. Detection and tracking of individual SNAP-tagged proteins on.

Distribution and functionality of Arch-EGFP pumps in the peripheral sensory pathways of Nav1.8-Arch+ mice. Distribution and functionality of Arch-EGFP.

Molecular Therapy - Methods & Clinical Development

TrkB-T1 is upregulated in cerebellum of Pex14ΔC/ΔC BL/ICR mouse at P3.

Expression of T-Cadherin in Basal Keratinocytes of Skin

BDNF expression in the cerebellum and brain stem region.

Alexandra Capela, Sally Temple Neuron

Impaired TrkB signaling in the cerebellum of Pex14ΔC/ΔC BL/ICR mice.

Volume 18, Issue 5, Pages (May 1997)

Rab3a and SNARE Proteins: Potential Regulators of Melanosome Movement

Single type II fibers visualized by intracellular labeling.

Przemysław B. Radwański et al. BTS 2016;1:

Identification of one type of RGCs with large somas.

Kasey L Jackson, Robert D Dayton, Ronald L Klein

Volume 17, Issue 18, Pages (September 2007)

Commissural Wt1+ neurons.

Volume 17, Issue 20, Pages (October 2007)

Expression of pcdh19 in BAC transgenic line.

Clonally derived neurosphere efficiently contributes to spinal cord regeneration and reconstitutes the whole complement of spinal cord cell types. Clonally.

Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.

Volume 98, Issue 3, Pages (August 1999)

NELAV RBPs are expressed in neurospheres and neural stem/progenitor cells in vitro. nELAV RBPs are expressed in neurospheres and neural stem/progenitor.

Subcellular localization of prestin and mutant proteins in type I, II and III cells. Subcellular localization of prestin and mutant proteins in type I,

Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.

The bHLH Transcription Factor Olig2 Promotes Oligodendrocyte Differentiation in Collaboration with Nkx2.2 Qiao Zhou, Gloria Choi, David J. Anderson

Lar function is not required for Stat92E accumulation in GSCs

Nigel P Pringle, Sarah Guthrie, Andrew Lumsden, William D Richardson

The adult female mouse ARC and VMH generate newborn neurons that respond to estrogens and leptin. The adult female mouse ARC and VMH generate newborn neurons.

RA signaling in early postnatal PFC

The expression pattern of marker proteins for sensory neuron subgroups changes during postnatal maturation. The expression pattern of marker proteins for.

Double immunostaining of P2X7R and cell-specific markers in morphine-tolerated rats. Double immunostaining of P2X7R and cell-specific markers in morphine-tolerated.

Macaque Satb2-RGCs are synaptically connected to geniculate neurons.

Lack of LC3–GFP clustering in neurons expressing mutant CHMP2B.

GFP is expressed selectively in NPY neurons.

Chronic sleep loss is associated with microglial phagocytosis.

MFN2 mutants induce abnormal mitochondrial clustering and morphology in cell bodies and proximal axons. MFN2 mutants induce abnormal mitochondrial clustering.

IHC detection of p-mTOR Ser 2448 in subcortical white matter during postnatal rat CNS development. IHC detection of p-mTOR Ser 2448 in subcortical white.

Domain 3, comprising the basolateral calyx and the stretch of axon leading to the heminode, selectively expressed NaV channels, KCNQ3, and certain scaffolding.

Expression of p130CAS in primary culture neurons

Identification of a novel subset of mDA neurons in the VTA that expresses Neurod6, OTX2, CALBINDIN1, ALDH1A1, and Grp. Identification of a novel subset.

Characterization of PvCre(Arbr); TaumGFP mice.

An ipRGC axon collateral colocalized with the presynaptic marker bassoon makes contact with TH-positive DAC processes. An ipRGC axon collateral colocalized.

ErbB4 expression in PV+ and PV– interneurons and the ErbB4 expression levels in hippocampus of WT and the NRG1tg-type-I mice. ErbB4 expression in PV+ and.

IR expression in the olfactory epithelium.

Selective expression of Neurod6 in mDA neurons in the VTA

Optogenetic analysis of mPFC neurons.

At 1 month, control and les rats were fed AL or fasted every other day for IF. Representative images of 1 μm sections, with electron micrograph insets.

CDCP1 colocalizes and interacts with MT1-MMP.

A tph2 promoter fragment labels DR serotonergic neurons.

Specificity of the WDR81 antibody for the antigen.

Lineage-specific decline of E2F1 nuclear levels during oligodendrocyte differentiation. Lineage-specific decline of E2F1 nuclear levels during oligodendrocyte.

ESCRT-0 component Hrs is an effector of Rab35.

Coexpression of Crf, Tac2, and Prkcd; and Sst, Tac2, and Prkcd (A-P -0

A Truncating Mutation of TRAPPC9 Is Associated with Autosomal-Recessive Intellectual Disability and Postnatal Microcephaly Ganeshwaran H. Mochida, Muhammad.

BDNF protein is expressed in neurons and astrocytes of hippocampus after pilocarpine-induced SE. A, Representative confocal images of hippocampal subfields.

Foxo3 is expressed in the adult mouse cochlea.

The bHLH Transcription Factor Olig2 Promotes Oligodendrocyte Differentiation in Collaboration with Nkx2.2 Qiao Zhou, Gloria Choi, David J. Anderson

Presentation transcript:

TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal region. TAG-1 is expressed by oligodendrocytes and accumulates at the juxtaparanodal region. A, In adult spinal cord sections, TAG-1 mRNA is expressed in small cells of the white matter (arrows, higher magnification inB). In the ventral horn TAG-1 is also detected in large, spindle-shaped neurons (arrowheads, higher magnification in B). C, In the white matter of adult spinal cord sections, TAG-1 protein is present in the soma of round to oval cells (green, arrows). D, In these cells, TAG-1 (green) colocalizes with APC (red), a marker for oligodendrocytes, as both channels overlap (yellow, arrows). E, TAG-1 also appears in clusters in white matter (red, arrows).F, Sequential labeling for paranodin/Caspr (green) shows that TAG-1 (red) has a discrete distribution and is concentrated in the juxtaparanode of myelinated fibers. G, TAG-1 protein is detected in myelin-rich membrane fractions isolated from adult spinal cord as a 135 kDa band and a 90 kDa adult isoform (lane 1). Whole protein extract from postnatal cerebellum was loaded in lane 2. Low levels of L1 protein are detected in the above myelin fractions (180 kDa band, lane 3). In these fractions, MBP (18.5 kDa band, lane 4) is abundantly expressed because it is detected in of the amount loaded inlanes 1 and 3. C, Ten images, 0.4 μm apart; D, 5 images, 0.4 μm apart; E,F, 11 images, 0.9 μm apart. Scale bars: A, C, D, 20 μm; B, E, F, 5 μm. Maria Traka et al. J. Neurosci. 2002;22:3016-3024 ©2002 by Society for Neuroscience