Figure 1 Segmentation of the normal-appearing periependymal white matter Segmentation of the normal-appearing periependymal white matter The figure demonstrates.

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Figure 1 Segmentation of the normal-appearing periependymal white matter Segmentation of the normal-appearing periependymal white matter The figure demonstrates the procedure to segment the normal-appearing periependymal white matter. First, the ventricles were segmented (A) and dilated by 1 mm to avoid partial volume effects and 2 mm to include the periependymal white matter (B). Second, the 1-mm dilated ventricle mask was subtracted from the 1 + 2 mm dilated ventricle mask (C). Finally, the periependymal mask was manually edited for smaller errors, and the lesion mask was subtracted (D) to overlay the final mask with T1 maps (E). Baptiste Pasquier et al. Neurol Neuroimmunol Neuroinflamm 2019;6:e541 Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.