Illustrative of aetiological mechanisms of large artery occlusion. Illustrative of aetiological mechanisms of large artery occlusion. (A) cardioembolism; (B) in situ thrombosis on atherosclerotic plaque with severe stenosis; (C) chronic atherosclerotic occlusion; (D) in situ thrombosis on atherosclerotic plaque with slight stenosis; (E) artery-to-artery embolism from in situ thrombus; (F) artery-to-artery embolism from atherosclerotic plaque; and (G) cardioembolism in combination with atherosclerotic stenosis. Chenglin Tian et al. Stroke Vasc Neurol 2017;2:244-250 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.