Figure 5 C5B3 inhibited inflammatory infiltration in an NMOSD mouse model in vivo C5B3 inhibited inflammatory infiltration in an NMOSD mouse model in vivo.

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Figure 5 C5B3 inhibited inflammatory infiltration in an NMOSD mouse model in vivo C5B3 inhibited inflammatory infiltration in an NMOSD mouse model in vivo (A) IBA1, CD45, and C5b-9 immunofluorescence staining showed inflammatory infiltration in the brain after the injection of IgGNMOSD and hC. The white lines delimit the IBA1-, CD45−, and C5b-9–positive areas. Scale bar is 500 μm. (B) Statistical data for IBA1−, CD45−, and C5b-9–positive areas. We used a 2-tailed unpaired t test to compare the 2 groups; n = 5/group; **p < 0.01. IBA1 = ionized calcium-binding adaptor molecule 1; NMOSD = neuromyelitis optica spectrum disorder. Wenli Zhu et al. Neurol Neuroimmunol Neuroinflamm 2019;6:e561 Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.