Roderick W Landymore, MD, Alexander J Bayes, MD, J

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Presentation transcript:

Preconditioning prevents myocardial stunning after cardiac transplantation  Roderick W Landymore, MD, Alexander J Bayes, MD, J.Thomas Murphy, MD, John H Fris, RT  The Annals of Thoracic Surgery  Volume 66, Issue 6, Pages 1953-1957 (December 1998) DOI: 10.1016/S0003-4975(98)00902-3

Fig 1 Experimental procedure and timeline. The aortic cross-clamp was removed after cold storage and transplantation (2 hours of ischemia). The heart was then allowed to beat for 60 minutes before terminating cardiopulmonary bypass. Hemodynamic measurements were performed at 90 and 150 minutes after releasing the aortic cross-clamp. Myocardial biopsies were taken at 90, 120, and 150 minutes after releasing the aortic cross-clamp. (Con = control group; HM+B = hemodynamic measurements and myocardial biopsies were taken; Pre-C = preconditioned animals; Pre-Bypass = measurements taken before cardiopulmonary bypass) The Annals of Thoracic Surgery 1998 66, 1953-1957DOI: (10.1016/S0003-4975(98)00902-3)