Immunohistochemical detection of nuclear and cytoplasmic YB-1 in osteosarcoma and synovial sarcoma. Immunohistochemical detection of nuclear and cytoplasmic.

Slides:

Advertisements

Similar presentations

Immunohistochemical staining for RXR subtypes within benign and endometrioid endometrial carcinoma. Immunohistochemical staining for RXR subtypes within.

Advertisements

A, baseline and 4-week PET scan from patient 2 (MET c

Significance of P53 and Rb protein expression in surgically treated non-small cell lung cancers Yung-Chie Lee, MD, PhD, Yih-Leong Chang, MD, Shi-Ping.

A, representative gross feature of a gastric cancer (arrows), an ulceroinfiltrative mass in the antral mucosa, arising in Pdx-1-Cre;Smad4F/F;Trp53F/F;Cdh1F/+

Dihydromyricetin decreases the sphere formation through downregulation of Sox2 in human osteosarcoma. Dihydromyricetin decreases the sphere formation through.

Effects of SC144 on in vivo ovarian tumor.

Representative images of immunohistochemical staining of discoidin domain receptor (DDR)2 in interstitial lung disease (ILD) other than idiopathic pulmonary.

Treatment of human MCC tumors with intralesional IFNβ is associated with MHC-I upregulation. Treatment of human MCC tumors with intralesional IFNβ is associated.

Expression of vascular endothelial growth factor in thoracic sarcomas

Bioluminescence imaging facilitates detection of tumor growth and metastasis in mouse orthotopic xenograft model. Bioluminescence imaging facilitates detection.

Knocking down Wnt3 increases the cells' response to trastuzumab and reduces cells' invasiveness. Knocking down Wnt3 increases the cells' response to trastuzumab.

The sesquiterpene lactone PN up-regulates MDM2 and p53 proteins.

Changes in tumor sizes, CA-125, serum ceruloplasmin, and copper levels in 5 patients with platinum-resistant high-grade epithelial ovarian cancer who received.

GA blocks HIF activity and reduces HIF target expression.

Immunohistochemical detection of 8-OHdG by use of the 1F7 monoclonal antibody in oligomer-treated PC3 prostate cancer cells. a, control untreated peripheral.

Cytotoxic activity of HER2-lytic hybrid peptide.

Activating mutation of Ras is associated with CDCP1 expression in NSCLC. A, NSCLC cell lines with Ras + B-Raf mutations and wild-type Ras were examined.

Immunohistochemical analyses of SHH expression levels in nonmalignant prostate and adenocarcinoma tissues. Immunohistochemical analyses of SHH expression.

Expression analysis of IGFBP-3 using human whole-genome microarray.

Change in antibody-dependent cellular cytotoxicity between baseline and day 15, day 30, and day 45 for cohort 1 and 2 versus cohort 3. Change in antibody-dependent.

Variation in dUTPase expression in cell lines.

Effect of HA on hematopoietic recovery in tumor-bearing mice.

A, cytotoxicity induced on HER2 3+ USC (ARK-2), HER2 0/1+ USC (ARK-4), and ARK-2/ARK-4 cocultures with 1 μg/mL of SYD985, T-DM1, and ADC isotype control.

GS87 demonstrates efficacy in a circulating AML mouse model system.

FAK overexpression in invasive human breast cancer and DCIS

Interaction of MAPJD with E-box sequence of the RIOK1 gene.

FAK overexpression in invasive human colon cancer and colon dysplasia.

Representative examples of estrogen receptor α and β immunohistochemical expression (top figures) and EGFR mutations (bottom figures) in lung adenocarcinomas.

Association between RB pathway alterations and poor prognosis in early-stage lung adenocarcinoma patients. Association between RB pathway alterations and.

Imatinib mesylate inhibits PDGF-mediated ERK and Akt activation.

Reduced BAI1 expression is associated with breast cancer patient survival. Reduced BAI1 expression is associated with breast cancer patient survival. A,

MAPJD expression in lung cancers.

Analysis of thermal stability and aggregation properties before and after disulfide stabilization of the pMHCI complex. Analysis of thermal stability and.

CAT displays very high in vivo stability as exemplified by a rat PK study. CAT displays very high in vivo stability as exemplified by a rat.

Accelerated metastasis spread in tumor-bearing mice treated with paclitaxel and anakinra. Accelerated metastasis spread in tumor-bearing mice treated with.

CD8, galectin-3, galectin-9, and the M1/M2 ratio are associated with a longer survival. CD8, galectin-3, galectin-9, and the M1/M2 ratio are associated.

In vivo thrombosis of tumor vasculature.

Correlation of miR-21 expression levels with DEGs in 28 bladder cancer cell lines. Correlation of miR-21 expression levels with DEGs in 28 bladder cancer.

Cisplatin plus PTUPB decreases proliferation and angiogenesis but increases apoptosis as determined by immunohistochemical (IHC) analysis. Cisplatin plus.

TDP1 and TOP1 protein levels vary widely in colorectal cancer (CRC) patient samples. TDP1 and TOP1 protein levels vary widely in colorectal cancer (CRC)

DNA damage-induced RPA foci in asynchronous cells labeled with BUdR.

Positive correlations between disease course and treatment-induced immune responses. Positive correlations between disease course and treatment-induced.

Clinical benefit from combination limb infusion and CTLA-4 blockade.

A, protein structure and functional domains of hdbpB/YB-1, hdbpA, hdbpC, NF-YA, NF-YB, and NF-YC. A, protein structure and functional domains of hdbpB/YB-1,

Endothelial cells/microvasucles are increased in prostate cancer versus normal tissues. Endothelial cells/microvasucles are increased in prostate cancer.

Curcumin suppresses the expression of antiapoptotic proteins in multiple myeloma cells. Curcumin suppresses the expression of antiapoptotic proteins in.

Angiogenesis in tumors formed by cells varying in the expression of CXCR2. Angiogenesis in tumors formed by cells varying in the expression of CXCR2. A,

Curcumin enhances effects of bortezomib to inhibit angiogenesis in multiple myeloma tumor samples. Curcumin enhances effects of bortezomib to inhibit angiogenesis.

Positions of the EGFR exon 20 insertions identified over a 3-year period and comparison with the spectrum of EGFR exon 19 and HER2 insertion mutations.

Paclitaxel treatment along with CXCR2 knockdown reduces tumor growth and metastasis. Paclitaxel treatment along with CXCR2 knockdown reduces tumor growth.

Immunohistochemical analysis of dUTPase in human breast adenocarcinoma

Tumor and serum levels of murine IL-12.

Effect of anti-cyCD79b (10D10) and anti-cyCD79b (10D10)-MCC-DM1 on cytokine levels in cynomolgus monkeys. Effect of anti-cyCD79b (10D10) and anti-cyCD79b.

Serial imaging before and after immunotherapy among patients with MDM2/4 amplifications (N = 6). Serial imaging before and after immunotherapy among patients.

Survival risk prediction analysis and application of the metastasis gene signature. Survival risk prediction analysis and application of the metastasis.

Ki-67 expression in M31- and H3-treated tumors (A) and respective Ki-67 labeling indices in the two groups of tumors (B). Ki-67 expression in M31- and.

Localization of oxidated thiols in A375 melanoma cells.

PTPH1 depends on its catalytic activity to increase ER nuclear accumulation and to enhance breast cancer sensitivity to TAM. A, effects of PTPH1 and PTPH1/DA.

CRA inhibits the growth of human tumor xenografts in vivo.

Extraction diagram of candidate genes identified by global expression analysis. Extraction diagram of candidate genes identified by global expression analysis.

Changes in signal transduction pathway induced by gefitinib.

Immunohistochemical staining for FOXO3a of breast cancer tumor tissues

Expression of versican promoted breast cancer cell tumor formation and self-renewal in vivo. Expression of versican promoted breast cancer cell tumor formation.

In situ analysis of human breast tissue shows the down-regulation of Spry isoforms in breast cancer. In situ analysis of human breast tissue shows the.

A 63-year-old female with lung adenocarcinoma treated with nivolumab, who experienced pseudoprogression. A 63-year-old female with lung adenocarcinoma.

Influence of ASGR2 expression on survival.

Histology (H&E; original magnification, ×100 for B-2P/C-12P/C-64P and ×40 for C-10P; top) of small-sized lung adenocarcinomas and immunohistochemical staining.

Specific reaction with MIB1, M30, and CD31 monoclonal antibodies in primary human cervical carcinoma before (A, C, and E) and after (B, D, and F) Tam treatment.

Detection of E-cadherin fragments in human prostate cancer metastases.

Immunohistochemical determination of TIM-3 expression in ccRCC.

Presentation transcript:

Immunohistochemical detection of nuclear and cytoplasmic YB-1 in osteosarcoma and synovial sarcoma. Immunohistochemical detection of nuclear and cytoplasmic YB-1 in osteosarcoma and synovial sarcoma. Antibodies were used against YB-1 (A, B, D, and E) or PGP (C and F). Osteosarcoma is shown with cytoplasmic YB-1 expression (A), nuclear YB-1 expression (B), and PGP expression (C). Synovial sarcoma is shown with cytoplasmic YB-1 expression (D), nuclear YB-1 expression (E), and PGP expression (F). The patient in D showed no evidence of disease 131 months after surgery. The patient in F died of lung metastasis 8 months after the initial surgery. Michihiko Kuwano et al. Mol Cancer Ther 2004;3:1485-1492 ©2004 by American Association for Cancer Research