Perfusing the Cold Brain: Optimal Neuroprotection for Aortic Surgery

Slides:

Advertisements

Similar presentations

The STS National Database

Advertisements

Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair Christian D. Etz, MD, PhD, Gabriele Di Luozzo, MD, Stefano.

The Completion Bentall Procedure

Deep Hypothermic circulatory arrest does not impair neurodevelopmental outcome in school-age children after infant cardiac surgery Stephanie Fuller,

Thoracic and Thoracoabdominal Aneurysm Repair: Is Reimplantation of Spinal Cord Arteries a Waste of Time? Christian D. Etz, MD, James C. Halstead, MA.

Hancock II Bioprosthesis for Aortic Valve Replacement: The Gold Standard of Bioprosthetic Valves Durability? Tirone E. David, MD, Susan Armstrong, MS,

Regulation of Brain Cell Death and Survival After Cardiopulmonary Bypass Tatiana Zaitseva, PhD, Steven Schultz, MD, Gregory Schears, MD, Peter Pastuszko,

Homograft Implantation Techniques in the Aortic Position: To Preserve or Replace the Aortic Root? Thanos Athanasiou, MD, PhD, Catherine Jones, MBBS,

Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery Farkas B. Vánky, MD, PhD, Erik.

Benjamin E. Lee, MD, Mark Shapiro, MD, John R. Rutledge, MAS, Robert J

Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat Sebastian.

Circulatory Arrest and Low-Flow Cardiopulmonary Bypass Alter CREB Phosphorylation in Piglet Brain Tatiana Zaitseva, PhD, Gregory Schears, MD, Steven.

Operative Results and Outcomes in Children With Shone's Anomaly

Newborn Aortic Arch Reconstruction With Descending Aortic Cannulation Improves Postoperative Renal Function James M. Hammel, MD, Joseph J. Deptula, MPS,

Response of Brain Oxygenation and Metabolism to Deep Hypothermic Circulatory Arrest in Newborn Piglets: Comparison of pH-Stat and Alpha-Stat Strategies

Simple Index to Predict Likelihood of Skilled Nursing Facility Admission After Coronary Artery Bypass Grafting Among Older Patients David C. Chang, PhD,

Subtypes of acute aortic dissection

Retrograde Cerebral Perfusion Is Effective for Prolonged Circulatory Arrest in Arch Aneurysm Repair Christopher Lau, MD, Mario Gaudino, MD, Erin Mills.

Axillary Cannulation Significantly Improves Survival and Neurologic Outcome After Atherosclerotic Aneurysm Repair of the Aortic Root and Ascending Aorta

Is the bentall procedure for ascending aorta or aortic valve replacement the best approach for long-term event-free survival? Christian Hagl, MD, Justus.

Resection of Intraabdominal Tumors With Cavoatrial Extension Using Deep Hypothermic Circulatory Arrest Christopher Lau, MD, Padraic O’Malley, MD, Mario.

James D. St. Louis, MD The Annals of Thoracic Surgery

Who Do You Say You Are? The Annals of Thoracic Surgery

Cardiac Output Augmentation During Hypoxemia Improves Cerebral Metabolism After Hypothermic Cardiopulmonary Bypass Jess M. Schultz, MD, Tara Karamlou,

The “Double-Valve” Sign in Acute Type A Aortic Dissection

Use of Amiodarone After Major Lung Resection

Masahiro Ono, MD, PhD, Charles Brown, MD, Jennifer K

Retrograde cerebral perfusion enhances cerebral protection during prolonged hypothermic circulatory arrest: a study in a chronic porcine model Tatu Juvonen,

Ivan Ricardo Argueta-Morales, MD, Hamish M

Christian Hagl, MD, Donald J. Weisz, PhD, Nawid Khaladj, MD, Matthew M

Hybrid Management of a Giant Left Main Coronary Artery Aneurysm

Percutaneous Transcatheter Closure of the Aortic Valve

The Utility of Electromagnetic Navigational Bronchoscopy as a Localization Tool for Robotic Resection of Small Pulmonary Nodules William D. Bolton, MD,

Gerald G.R. Sng, Cameron D. Wright, MD The Annals of Thoracic Surgery

Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair Stefano Zoli, MD, Fabian Roder, MS, Christian D. Etz, MD, PhD,

W. Brent Keeling, MD, David H. Tian, MD, PhD, Brad G

Aortic Arch Repair With Antegrade Selective Cerebral Perfusion Using Mild to Moderate Hypothermia of More Than 28°C Satoshi Numata, MD, PhD, Yasushi.

Andreas Zierer, MD, Marc R. Moon, MD, Spencer J

Impact of Residency Status on Perfusion Times and Outcomes for Coronary Artery Bypass Graft Surgery Constance K. Haan, MD, Sarah Milford-Beland, MS,

Editorial Board, January 2010

Sarah C. Huen, MD, Chirag R. Parikh, MD, PhD

Understanding Mortality as a Quality Indicator After Esophagectomy

Christian D. Etz, MD, Tobias M

Hypothermic Low-Flow Cardiopulmonary Bypass Impairs Pulmonary and Right Ventricular Function More Than Circulatory Arrest Jess M. Schultz, MD, Tara Karamlou,

Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs Justus T. Strauch, MD, Peter.

Completely Thrombosed Tricuspid Pouch Mimicking a Cardiac Tumor

Spinal Cord Perfusion and Protection During Descending Thoracic and Thoracoabdominal Aortic Surgery: The Collateral Network Concept Randall B. Griepp,

Current Assessment of Mortality Rates in Congenital Cardiac Surgery

Deterioration of a Tricuspid Bioprosthesis Due to Adhesion of the Native Valve Herbert Gutermann, MD, Willem Flameng, MD, PhD, Paul Herijgers, MD, PhD

Jorge D. Salazar, MD, Ryan D

Aortic arch replacement using a trifurcated graft and selective cerebral antegrade perfusion David Spielvogel, MD, Justus T Strauch, MD, Oktavijan P.

Ascending Aortic Pseudoaneurysm as an Unusual Cause of Superior Vena Cava Syndrome Zhiqi Zhang, MD, Kanhua Yin, MD, Yongxin Sun, MD, PhD, Chunsheng Wang,

The fate of the distal aorta after repair of acute type A aortic dissection James C. Halstead, MA (Cantab), MB, BChir, MRCS (Eng), Matthias Meier, MD,

Invited Commentary The Annals of Thoracic Surgery

Robert Lee Replogle, September 30, 1931–May 9, 2016

The American Board of Thoracic Surgery: Update

Stefano Zoli, MD, Christian D

“Transitions” for Cardiothoracic Surgeons Now Listed on the Web:

Platelet-activating factor receptor antagonism improves cerebral recovery after circulatory arrest Stephen M Langley, Paul J Chai, MD, James J Jaggers,

Mark I. Block, MD The Annals of Thoracic Surgery

Late Consequences of a Much Earlier Decision

An Assay to Monitor Bivalirudin Levels on Cardiopulmonary Bypass

The Impact of New Technology on Cardiothoracic Surgical Practice

Frank G. Scholl, MD, David Webb, CCP, Karla Christian, MD, Davis C

Effect of hypothermia on cerebral blood flow and metabolism in the pig

Marek P. Ehrlich, MDa, Christian Hagl, MDa, Jock N

Leukocytosis and Increased Risk of Atrial Fibrillation After General Thoracic Surgery David Amar, MD, Anuj Goenka, BS, Hao Zhang, MD, Bernard Park, MD,

David Spielvogel, MD, James C

Harvey Edward Garrett, MD, Bradley A. Wolf, MD

Presentation transcript:

Perfusing the Cold Brain: Optimal Neuroprotection for Aortic Surgery James C. Halstead, MA, MRCS, Christian Etz, MD, D. Matthias Meier, MD, Ning Zhang, MD, David Spielvogel, MD, Donald Weisz, PhD, Carol Bodian, DrPH, Randall B. Griepp, MD The Annals of Thoracic Surgery Volume 84, Issue 3, Pages 768-774 (September 2007) DOI: 10.1016/j.athoracsur.2007.04.051 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Cerebral blood flow rates (mean values ± SE): group A (black bars), hypothermic circulatory arrest (HCA); group B (shaded bars), HCA/selective cerebral perfusion (SCP); and group C (white bars), SCP. The Annals of Thoracic Surgery 2007 84, 768-774DOI: (10.1016/j.athoracsur.2007.04.051) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Cerebral metabolic rate for oxygen (mean values ± SE): group A (black bars), hypothermic circulatory arrest (HCA); group B (shaded bars), HCA/selective cerebral perfusion (SCP); and group C (white bars), SCP. The question marks indicate the HCA time points at which it was not possible to measure cerebral metabolic rate for oxygen (CMRO2). The Annals of Thoracic Surgery 2007 84, 768-774DOI: (10.1016/j.athoracsur.2007.04.051) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Results from the videotaped analysis of pig motor behavior (median values): group A (solid line with diamonds), deep hypothermic circulatory arrest (DHCA); group B (dashed line with squares), DHCA/selective cerebral perfusion (SCP); and group C (dotted line with circles), SCP. The Annals of Thoracic Surgery 2007 84, 768-774DOI: (10.1016/j.athoracsur.2007.04.051) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions