Figure 2. Forest plot of multivariable Cox proportional hazard regression illustrating the impact of chemoradiation ... Figure 2. Forest plot of multivariable.

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Figure 2. Forest plot of multivariable Cox proportional hazard regression illustrating the impact of chemoradiation ... Figure 2. Forest plot of multivariable Cox proportional hazard regression illustrating the impact of chemoradiation versus radiation alone on overall survival. P-values are shown for tests of interaction between the effect of postoperative chemoradiation and a given covariate. HR, hazard ratio; ENE, extranodal extension. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Ann Oncol, Volume 30, Issue 1, 05 November 2018, Pages 76–84, https://doi.org/10.1093/annonc/mdy490 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 3. Kaplan–Meier curves comparing propensity-score-matched cohorts of patients receiving postoperative ... Figure 3. Kaplan–Meier curves comparing propensity-score-matched cohorts of patients receiving postoperative chemoradiation versus radiation alone in non-oropharyngeal head and neck squamous cell carcinoma patients with (A) 0–2 positive lymph node (LN), (B) 3–5 positive LN, and (C) ≥6 positive LN. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Ann Oncol, Volume 30, Issue 1, 05 November 2018, Pages 76–84, https://doi.org/10.1093/annonc/mdy490 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 4. Forest plot of the effect of postoperative chemoradiation versus radiation alone in patients with varying ... Figure 4. Forest plot of the effect of postoperative chemoradiation versus radiation alone in patients with varying numbers of positive lymph nodes in the subgroup of patients with classic high-risk features: positive margins, extranodal extension, or both. RT, postoperative radiotherapy. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Ann Oncol, Volume 30, Issue 1, 05 November 2018, Pages 76–84, https://doi.org/10.1093/annonc/mdy490 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 1. Smoothed restricted cubic spline plot of the adjusted hazard ratio (HR) of the effect of postoperative ... Figure 1. Smoothed restricted cubic spline plot of the adjusted hazard ratio (HR) of the effect of postoperative chemoradiation (CRT) versus radiation alone (RT) on survival as a function of the number of metastatic cervical lymph nodes. Predicted HRs were estimated from a proportional hazards model adjusting for covariates. Change points were identified at two positive lymph nodes (LNs) and five positive LNs. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Ann Oncol, Volume 30, Issue 1, 05 November 2018, Pages 76–84, https://doi.org/10.1093/annonc/mdy490 The content of this slide may be subject to copyright: please see the slide notes for details.