Flies Sleep on It, or Fuhgeddaboudit!

Slides:

Advertisements

Similar presentations

How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni

Advertisements

The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation Akinobu Suzuki, Sarah A. Stern, Ozlem Bozdagi, George W. Huntley, Ruth H.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry Xing Zhang, Lei Jin, Qin Fang, Wong H. Hui, Z. Hong Zhou Cell.

Treatment of Obesity with Celastrol

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,

Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies B.J. Casey, Charles E. Glatt, Francis S. Lee Neuron Volume.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.

Predicting C4 Photosynthesis Evolution: Modular, Individually Adaptive Steps on a Mount Fuji Fitness Landscape David Heckmann, Stefanie Schulze, Alisandra.

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology Andrew G. Manford, Christopher J. Stefan, Helen L. Yuan, Jason A. MacGurn,

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,

Writing Memories with Light-Addressable Reinforcement Circuitry Adam Claridge-Chang, Robert D. Roorda, Eleftheria Vrontou, Lucas Sjulson, Haiyan Li, Jay.

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

A DNA-Dependent Protease Involved in DNA-Protein Crosslink Repair Julian Stingele, Michael S. Schwarz, Nicolas Bloemeke, Peter G. Wolf, Stefan Jentsch.

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure Jerome Solon, Aynur Kaya-Çopur, Julien Colombelli,

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

The Search for Antiaging Interventions: From Elixirs to Fasting Regimens Rafael de Cabo, Didac Carmona-Gutierrez, Michel Bernier, Michael N. Hall, Frank.

Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,

Rare Inherited Variation in Autism: Beginning to See the Forest and a Few Trees Jason L. Stein, Neelroop N. Parikshak, Daniel H. Geschwind Neuron Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Volume 1, Issue 1, Pages (June 2007)

Unweaving the Autism Spectrum

Volume 154, Issue 1, Pages (July 2013)

In This Issue Cell Volume 158, Issue 5, (August 2014)

With Happyhour, Everyone's Under the Table

Monkey Research in China: Developing a Natural Resource

Volume 152, Issue 1, (January 2013)

Monkey Research in China: Developing a Natural Resource

Volume 130, Issue 6, (September 2007)

Do Flies Count Sheep or NMDA Receptors to Go to Sleep?

Need for Speed: Mechanical Regulation of a Replicative Helicase

Easy Stress Relief by EZH2

Volume 143, Issue 6, (December 2010)

Volume 166, Issue 4, Pages (August 2016)

Making the Most from Changes in Life

Rac in the Act of Forgetting

Learning from the Uncontrollable

Volume 163, Issue 4, (November 2015)

Immune Cells Exploit a Neural Circuit to Enter the CNS

Volume 163, Issue 2, (October 2015)

Volume 134, Issue 6, (September 2008)

In This Issue Cell Volume 145, Issue 3, (April 2011)

Volume 148, Issue 1, (January 2012)

Targeting Protein Stability with a Small Molecule

Presentation transcript:

Flies Sleep on It, or Fuhgeddaboudit! Jason Rihel, Daniel Bendor Cell Volume 161, Issue 7, Pages 1498-1500 (June 2015) DOI: 10.1016/j.cell.2015.06.011 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Flies that Have Learned to Associate Electric Shocks with a Neutral Odor Will Subsequently Remember to Avoid the Odor The erosion of this memory is actively regulated by a dopamine circuit (DAN) in the fly brain. During arousal, DAN activity is high and enhances forgetting. During sleep, DAN activity is low and forgetting is decreased. Cell 2015 161, 1498-1500DOI: (10.1016/j.cell.2015.06.011) Copyright © 2015 Elsevier Inc. Terms and Conditions