Formation of complex antibiotic resistance regions. Formation of complex antibiotic resistance regions. (A) Structure of Tn6026. (B) Building transposons using TUs derived from Tn4352 and Tntet(D). The origin of each IS26-bounded structure is shown above. Genes and open reading frames are shown as arrows indicating the direction of transcription. Genes conferring antibiotic resistance are black. IS26 elements are shown as open boxes with an arrow indicating the position and orientation of tnp26. Christopher J. Harmer, and Ruth M. Hall mSphere 2016; doi:10.1128/mSphere.00038-16