Would it be more beneficial to take aspirin in the evening for prevention of cardiovascular diseases?  Ildikó Kriszbacher, MSC, Miklós Koppán, MD, PhD,

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Would it be more beneficial to take aspirin in the evening for prevention of cardiovascular diseases?  Ildikó Kriszbacher, MSC, Miklós Koppán, MD, PhD, József Bódis, MD, PhD, DSc  Journal of Vascular Surgery  Volume 41, Issue 2, (February 2005) DOI: 10.1016/j.jvs.2004.10.051 Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

Fig Relation of plasma serum levels of salicylic acid and the daily distribution of the occurrence of myocardial infarction and of acute ischemic stroke. Vertical bar graphs represent daily distribution of the incidence of myocardial infarction and stroke.2,3 Line diagrams show the serum levels of salicylic acid in μg/mL taken at 10:00 pm (dotted line) and at 8:00 am (solid line). The maximum plasma concentration of salicylic acid occurs 3.5 to 4.0 hours after intake.4 •Myocardial infarct (n = 914), —stroke (n = 1741); n, total number of patients involved in analysis; SA, salicylic acid. Journal of Vascular Surgery 2005 41, DOI: (10.1016/j.jvs.2004.10.051) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions