Fig. 3 Echocardiographic analyses of cardiac function. Echocardiographic analyses of cardiac function. (A) Schematic representation of the work flow using zECM (0.5 mg of suspension) for mammalian heart regeneration after AMI. Cardiac contractile function is indicated by (B) fractional area change and (C) ejection fraction; LV dimension is indicated by (D) EDA and (E) ESA (n = 7 per group; data analyzed by two-way repeated-measures analysis of variance (ANOVA); *P ≤ 0.05, †P ≤ 0.01, §P ≤ 0.005, #P ≤ 0.001 compared to saline controls in all graphs). William C. W. Chen et al. Sci Adv 2016;2:e1600844 Copyright © 2016, The Authors