Concurrent Metastatic Thymic Carcinoma and Postirradiation Sarcoma

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Concurrent Metastatic Thymic Carcinoma and Postirradiation Sarcoma Tzu-Ju Chen, MD, Hung-I. Lu, MD, Cheng-Hua Huang, MD, Hsuan-Chih Hsu, MD, Sung-Ting Chen, MD, Wei-jen Chen, MD, Chao- Cheng Huang, MD  The Annals of Thoracic Surgery  Volume 93, Issue 4, Pages 1295-1296 (April 2012) DOI: 10.1016/j.athoracsur.2011.09.046 Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Computed tomographic scans. (A) One subpleural pulmonary tumor is present at the inferior portion of the right upper lobe (arrow). (B) Another subpleural tumor is present at the apical region of the same lobe (arrow). The Annals of Thoracic Surgery 2012 93, 1295-1296DOI: (10.1016/j.athoracsur.2011.09.046) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Microscopic features of the pulmonary nodules. (A) The subpleural pulmonary tumor at the inferior portion of the right upper lobe is composed of nests of neoplastic epithelial cells bearing pleomorphic, vesicular nuclei and prominent nucleoli (inset). (B) These tumor cells are positive for CD5. (C) The apical tumor has an infiltrative border and is composed of neoplastic spindle cells with pleomorphic nuclei. An atypical mitosis is shown (inset). (D) The CD5 immunostaining highlights the lymphocytes but not the tumor cells. (A) and (C), hematoxylin & eosin, original magnification 40×, inset 400×; (B) and (D), immunohistochemistry, original magnification 400×. The Annals of Thoracic Surgery 2012 93, 1295-1296DOI: (10.1016/j.athoracsur.2011.09.046) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions