Triclosan-gavaged rats are more susceptible to S

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Triclosan-gavaged rats are more susceptible to S Triclosan-gavaged rats are more susceptible to S. aureus nasal colonization. Triclosan-gavaged rats are more susceptible to S. aureus nasal colonization. Cotton rats were gavaged with triclosan or an oil control for 3 days. On day 5, they were challenged with either a small inoculum (105 CFU) or a large inoculum (108 CFU) of S. aureus. On day 12, their noses were removed and S. aureus bacteria were enumerated. Rats gavaged with triclosan were unable to clear the small inoculum, whereas the oil-gavaged rats were able to clear the bacteria from their noses. *, P < 0.01 by t test. Adnan K. Syed et al. mBio 2014; doi:10.1128/mBio.01015-13