Discovered and replicated positive correlation between miR-193b

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Discovered and replicated positive correlation between miR-193b Discovered and replicated positive correlation between miR-193b* expression and platinum sensitivity. Discovered and replicated positive correlation between miR-193b* expression and platinum sensitivity. A and B, the relationship between miR-193b* expression on the one hand and carboplatin (A) and cisplatin (B) IC50 on the other in the discovery-phase CEU samples, respectively. C and D, the relationship between miR-193b* expression on the one hand and carboplatin (C) and cisplatin (D) IC50 on the other in the replication CEU samples, respectively. Exiqon arrays were used to obtain miRNA expression data in the discovery-phase samples, whereas real-time PCR method was used to quantify miRNA expression in the replication samples. Dana Ziliak et al. Mol Cancer Ther 2012;11:2054-2061 ©2012 by American Association for Cancer Research