Black dots in palmoplantar warts—challenging a concept: A histopathologic study Isabella Fried, MD, Romano Silvio Kasper, MD, Ivan Hegyi, MD, Werner Kempf,

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Presentation transcript:

Black dots in palmoplantar warts—challenging a concept: A histopathologic study Isabella Fried, MD, Romano Silvio Kasper, MD, Ivan Hegyi, MD, Werner Kempf, MD Journal of the American Academy of Dermatology Volume 79, Issue 2, Pages 380-382 (August 2018) DOI: 10.1016/j.jaad.2018.01.013 Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Absence of intravascular microthrombi and detection of intracorneal hemorrhages in warts. No intravascular thrombi could be detected on hematoxylin-eosin (HE)-stained sections and with use of CD61 antibody, as is demonstrated in this representative wart from the finger. However, intracorneal hemorrages (arrows) were found in the majority of warts and could be highlighted by benzidine stain, as is shown in this plantar wart. (Original magnifications: HE stain, ×5 and ×20; CD61, ×4 and ×20; and benzidine stain, ×2 and ×10.) Journal of the American Academy of Dermatology 2018 79, 380-382DOI: (10.1016/j.jaad.2018.01.013) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Curettage of a plantar wart. Clinical picture of a typical plantar wart with black dots before and after superficial curettage. Note that the number of black dots was significantly reduced by the procedure. The curettage material showed only a cornified layer of the epidermis and intracorneal hemorrhages (arrows) with use of hematoxylin-eosin (HE) and benzidine stain. (Original magnifications: ×10.) Journal of the American Academy of Dermatology 2018 79, 380-382DOI: (10.1016/j.jaad.2018.01.013) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions