R. Nicholas Nolte, MD1, Ravishankar Hasanadka, MD2 Effects of Body Mass Index on Fluoroscopy Time in Peripheral Vascular Interventions for Arterial Occlusive Disease in the Mid-America Vascular Study Group R. Nicholas Nolte, MD1, Ravishankar Hasanadka, MD2 1OSF St. Francis Medical Center, Peoria, IL; 2Southern Illinois University, Springfield, IL Background Endovascular interventions present an attractive alternative to open revascularization as a means to reduce hospital stay, morbidity, and mortality1. Current trends show a steady increase in endovascular interventions performed for lower extremity peripheral arterial disease, with a steady decline in open revascularization and amputation2. Increased complexity of interventions results in increased fluoroscopy time (FT) and radiation exposure to the interventionalist, patient, and staff3. Body mass index (BMI) has been found to correlate with physician radiation dose in coronary angiography as well as increased patient radiation exposure in lower extremity interventions4-5. Results Discussion Consider brachial, radial, or pedal access compared to femoral access if applicable in obese patients (BMI >30) to significantly lower FT Higher FT in obese patients with more complex lesions, TASC C/D FT increases with more complex procedures and is correlated with increased estimated skin dose (ESD)6 Reduce risk for tissue injury to the patient by using less cineangiography, close the collimators to limit dose area, consider rotating the angle of the image-intensifier to change the beam path 1 in 14 patients undergoing lower extremity interventions are exposed to radiation doses which could potentially lead to tissue injury4 Reduce operator exposure by using maximum shielding to reduce effects of scatter: table aprons, portable shields, rad pads Cumulative FT of 1404 minutes and DAP of 932000 mGy/cm2 was found to result in a critical eye lense radiation dose of 20 mSv/year7 Limitations: Retrospective nature of database could lead to missing data or inaccuracies DAP values were not entered consistently in the same units of measure across centers in the PVI registry. Therefore, this data could not be analyzed. Table 1. Summary of Multiple Linear Regression Model: Effects of Covariates on Fluoroscopy Times. Estimate Std. Error t-value (p-value) Confidence Interval (95%) Covariates Age 0.006 0.003 2.290(0.022)* 0.001 / 0.011 Race (White) -0.165 0.071 -2.313(0.021)* -0.306 / -0.025 BMI 0.019 0.007 2.567(0.010)* 0.005 / 0.034 Smoking (Current/Former) -0.171 0.079 -2.159(0.031)* -0.326 / -0.016 CHF (Yes) 0.407 0.128 3.178(0.002)** 0.156 / 0.658 Diabetes (None) -0.091 0.053 -1.710(0.087) -0.195 / 0.013 Diabetes (No Meds) 0.083 0.089 0.933(0.351) -0.092 / 0.258 Diabetes (Meds) 0.008 0.144(0.885) -0.096 / 0.111 Aortoiliac (vs infrainguinal) Treatment Site -0.684 -9.663(0.000)*** -0.823 / -0.545 Previously Treated (Yes) -0.150 0.058 -2.608(0.009)** -0.263 / -0.037 Calcification (Low) -0.442 0.054 -8.121(0.000)*** -0.549 / -0.335 Access Type (Femoral) 0.038 0.148 0.253(0.800) -0.253 / 0.329 TASC Classification (A/B) -0.306 0.057 -5.342(0.000)*** -0.418 / -0.194 Number Access Sites (2) 0.620 0.098 6.338(0.000)*** 0.428 / 0.812 Number Devices (2) 0.042 0.032 1.316(0.188) -0.020 / 0.104 Number Devices (3) 0.186 0.020 9.181(0.000)*** 0.146 / 0.226 Interaction Terms BMI * Access (Femoral) 0.055 0.024 2.269(0.023)* 0.007 / 0.102 BMI * TASC (A/B) -0.028 0.009 -2.976(0.003)** -0.046 / -0.009 Objective This study seeks to evaluate the effect of BMI on FT in lower extremity peripheral vascular interventions for arterial occlusive disease using regional data collected using the Society for Vascular Surgery Vascular Quality Initiative (VQI). Conclusions Methods Retrospective database review IRB exemption status obtained from the OSF Healthcare IRB Procedural data recorded in the PVI registry of the VQI Mid-America Vascular Study Group from January 2012 to December 2018 (n = 9,638) Procedures limited to treatment of one vessel (aortoiliac & infrainguinal) for occlusive disease with relevant data points were included (n = 1,436) Outcome variables tested initially included FT, dose area product (DAP), and contrast volume used during the procedure. Only FT was used for the final analysis Linear regression was used for univariate and multivariate analyses to assess the effect of patient and procedural variables on FT. Increasing BMI significantly increases FT when treating TASC C/D lesions or in procedures with femoral access. Our study highlights an opportunity to improve data entry and analysis in the PVI module in regard to DAP recording Fluoroscopy Time with BMI and TASC classification Fluoroscopy Time with BMI and access site References Sigterman TA, Bolt LJJ, Snoeijs MG, et al. Radiation Exposure during Percutaneous Transluminal Angioplasty for Symptomatic Peripheral Arterial Disease. Annals of Vascular Surgery. 2016;33:167-172. Hong MS, Beck Aw Fau - Nelson PR, Nelson PR. Emerging national trends in the management and outcomes of lower extremity peripheral arterial disease. J Vasc Surg. 2017 January ; 65(1): 108–118 Walsh SR, Cousins C Fau - Tang TY, Tang Ty Fau - Gaunt ME, Gaunt Me Fau - Boyle JR, Boyle JR. Ionizing radiation in endovascular interventions. J Endovasc Ther 2008;15:680–687. Goldsweig AM, Kennedy KF, Abbott JD, et al. Patient Radiation Dosage During Lower Extremity Endovascular Intervention. JACC: Cardiovascular Interventions. 2019;12(5):473. 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