Cytotoxic activity of CD8+ T-cells stimulated with SSX2-derived p

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Presentation transcript:

Cytotoxic activity of CD8+ T-cells stimulated with SSX2-derived p103-111. Cytotoxic activity of CD8+ T-cells stimulated with SSX2-derived p103-111. The lytic activity of T-cells was tested in a europium release assay. Specific lysis is shown at the indicated effector to target cell ratios, using 1000 labeled T2 cells as targets. Cells were pulsed with SSX2 p103-111 (filled boxes) or a control peptide (empty boxes). T-cells specific for the influenza matrix protein (IMP) derived peptide p58-66 were used as positive controls. Shown is the lysis of T2 cells loaded with IMP p58-66 (filled circles) or a control peptide (empty circles). Claudia Wagner et al. Cancer Immun 2003;3:18 Copyright © 2003 by Michael Pfreundschuh