Illustration highlighting the ‘sponge’ analogy for the role for sex hormone binding globulin (SHBG) in reducing luteinising hormone (LH)-dependent thecal.

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Presentation transcript:

Illustration highlighting the ‘sponge’ analogy for the role for sex hormone binding globulin (SHBG) in reducing luteinising hormone (LH)-dependent thecal androgen (A) availability, and the link of SHBG to weight and to the increase in free androgen when its level reduces. Illustration highlighting the ‘sponge’ analogy for the role for sex hormone binding globulin (SHBG) in reducing luteinising hormone (LH)-dependent thecal androgen (A) availability, and the link of SHBG to weight and to the increase in free androgen when its level reduces. This does not affect follicle-stimulating hormone (FSH)-stimulated estradiol (E) secretion. See text for an explanation of stages a–i. W Colin Duncan J Fam Plann Reprod Health Care 2014;40:217-225 Copyright © by the BMJ Publishing Group Ltd & the Faculty of Sexual & Reproductive Healthcare of the Royal College of Obstetricians & Gynaecologists. All rights reserved.